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InventoryRef 3380015/10/2010

ETHANOLAMINE THIOGLYCOLATE

(2-Hydroxyethyl)ammonium mercaptoacetate

ETHANOLAMINE THIOGLYCOLATE is linked to 2 EU annex records on this page. Inventory note: III/2a III/61.

Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence
2English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 126-97-6
CAS 126-97-6PubChem CID 160430

Monoethanolamine thioglycolate

Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Cosmetic Ingredient Review (CIR)

IUPAC name
2-aminoethanol;2-sulfanylacetic acid
Molecular formula
C4H11NO3S
Molecular weight
153.20 g/mol
Exact mass
153.04596439 Da
Topological polar surface area
84.6 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
5
Covalent units
2
Defined stereocentres
0

Also known as

Ethanolamine thioglycolate(2-Hydroxyethyl)ammonium mercaptoacetateEINECS 204-815-4EC 204-815-4263SH5220TTHIOGLYCOLIC ACID MONOETHANOLAMINE SALTN-(2-HYDROXYETHYL)AMMONIUM THIOGLYCOLATEETHANOL, 2-AMINO-, MERCAPTOACETATE (SALT)
10 more reported names
RefChem:819297ETHANOLAMINE THIOGLYCOLATE [INCI]UNII-263SH5220TEthanolamine thioglycolate (ca. 85% in water)2-aminoethanol,2-sulfanylacetic acidEthanolamine MercaptoacetateXTJCJAPNPGGFED-UHFFFAOYSA-NAS-75819Sulfanylacetic acid--2-aminoethan-1-ol (1/1)Ethanolamine thioglycolate (~85% in water), AldrichCPR
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match160430

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (39.1%): May be corrosive to metals [Warning Corrosive to Metals]; H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H315 (60.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (39.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (60.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P234, P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Cosmetic Ingredient Review Conclusion: Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ETHANOLAMINE THIOGLYCOLATE

INCI name

ETHANOLAMINE THIOGLYCOLATE

Description

(2-Hydroxyethyl)ammonium mercaptoacetate

Record provenance

Inventory reference
33800
Imported identity
ETHANOLAMINE THIOGLYCOLATE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
III/2a III/61
Function
DEPILATORY
Breaking down the mechanical strength of hair fibers so that they can be removed by mild scraping/rubbing.
HAIR WAVING OR STRAIGHTENING
Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).
REDUCING
Changing the chemical nature of another ingredient by adding hydrogen (or removing oxygen).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How ETHANOLAMINE THIOGLYCOLATE appears in the CosIng inventory

The CosIng inventory lists ETHANOLAMINE THIOGLYCOLATE as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ETHANOLAMINE THIOGLYCOLATE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ETHANOLAMINE THIOGLYCOLATE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for ETHANOLAMINE THIOGLYCOLATE reads: "III/2a III/61". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, ETHANOLAMINE THIOGLYCOLATE carries the following function designation(s):

CAS 126-97-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for ETHANOLAMINE THIOGLYCOLATE

This page combines the CosIng inventory entry for ETHANOLAMINE THIOGLYCOLATE with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research ETHANOLAMINE THIOGLYCOLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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