ETHANOLAMINE THIOGLYCOLATE
(2-Hydroxyethyl)ammonium mercaptoacetate
ETHANOLAMINE THIOGLYCOLATE is linked to 2 EU annex records on this page. Inventory note: III/2a III/61.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Restricted entry found Open this evidence | 2 | English and EU languages |
| Great Britain | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties

Monoethanolamine thioglycolate
Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. — Cosmetic Ingredient Review (CIR)
- IUPAC name
- 2-aminoethanol;2-sulfanylacetic acid
- Molecular formula
- C4H11NO3S
- Molecular weight
- 153.20 g/mol
- Exact mass
- 153.04596439 Da
- Topological polar surface area
- 84.6 Ų
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 5
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
10 more reported names
External database identifiers
- EPA DTXSID:DTXSID7059569
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H290 (39.1%): May be corrosive to metals [Warning Corrosive to Metals]; H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H315 (60.9%): Causes skin irritation [Warning Skin corrosion/irritation]; H317 (39.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H319 (60.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P234, P261, P264, P264+P265, P270, P272, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Cosmetic Ingredient Review Conclusion: Based on the available data, the CIR Expert Panel concluded that ... Ethanolamine Thioglycolate is safe for use in hair straighteners, permanent waves, tonics, dressings, and so forth, wave sets, other non-coloring hair products, and hair dyes and colors, as described in this safety assessment, at concentrations up to 15.2% (as Thioglycolic Acid). Hairdressers should avoid skin contact and minimize consumer skin exposure. Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Chelating agent Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Cleaning agent Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Ethanolamine Thioglycolate Source: Cosmetic Ingredient Review (CIR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for ETHANOLAMINE THIOGLYCOLATE
INCI name
ETHANOLAMINE THIOGLYCOLATE
Description
(2-Hydroxyethyl)ammonium mercaptoacetate
Record provenance
- Inventory reference
- 33800
- Imported identity
- ETHANOLAMINE THIOGLYCOLATE
- Source update
- 15/10/2010
Annex records for ETHANOLAMINE THIOGLYCOLATE
Key data
- DEPILATORY
- Breaking down the mechanical strength of hair fibers so that they can be removed by mild scraping/rubbing.
- HAIR WAVING OR STRAIGHTENING
- Modifying the chemical structure of the hair, allowing it to be set in the style required (permanent waves or hair straightening).
- REDUCING
- Changing the chemical nature of another ingredient by adding hydrogen (or removing oxygen).
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How ETHANOLAMINE THIOGLYCOLATE appears in the CosIng inventory
The CosIng inventory lists ETHANOLAMINE THIOGLYCOLATE as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
ETHANOLAMINE THIOGLYCOLATE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for ETHANOLAMINE THIOGLYCOLATE
This page combines the CosIng inventory entry for ETHANOLAMINE THIOGLYCOLATE with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research ETHANOLAMINE THIOGLYCOLATE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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