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CAS 538-71-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3374015/10/2010

DOMIPHEN BROMIDE

1-Dodecanaminium, N,N-dimethyl-N-(2-phenoxyethyl)-, bromide

DOMIPHEN BROMIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 538-71-6

CAS 538-71-6PubChem CID 10866

Domiphen Bromide

Domiphen bromide is an aromatic ether. — ChEBI

IUPAC name: dodecyl-dimethyl-(2-phenoxyethyl)azanium bromide

Molecular formula: C22H40BrNO
Molecular weight: 414.5 g/mol
Exact mass: 413.22933 Da
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 2
Defined stereocentres: 0

Also known as

OradolPhenododecinium bromideNSC-39415Bromuro de domifenoBromure de domiphene1-Dodecanaminium, N,N-dimethyl-N-(2-phenoxyethyl)-, bromideDomipheni bromidumR4CY19YS7C

16 more reported names

Dodecyldimethyl(2-phenoxyethyl)ammonium bromidedomifene bromuroRefChem:590363A01AB06208-702-0Domiphen (bromide)BradasolFungitexN,N-dimethyl-N-(2-phenoxyethyl)dodecan-1-aminium bromideBradonitBradoralBradosol bromideFungitex Rdodecyldimethyl(2-phenoxyethyl)azanium bromide1-Dodecanaminium, N,N-dimethyl-N-(2-phenoxyethyl)-, bromide (1:1)CAS-538-71-6

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:31514
ChEMBL:CHEMBL486696
EPA DTXSID:DTXSID5033468
PubMed:1028

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DOMIPHEN BROMIDE

INCI name

DOMIPHEN BROMIDE

INN name

domiphen bromide

Description

1-Dodecanaminium, N,N-dimethyl-N-(2-phenoxyethyl)-, bromide

Record provenance

Inventory reference: 33740
Imported identity: DOMIPHEN BROMIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DOMIPHEN BROMIDE

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Key data

CAS

538-71-6

208-702-0

Restriction

—

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.
ANTIPLAQUE: Helping protect against plaque.
DEODORANT: Reducing and/or eliminating unpleasant odour. Contributing against the formation of malodour on body surfaces.
ORAL CARE: Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9604 · DOMIPHEN BROMIDE

Ingredients with overlapping formulation functions

CINNAMOMUM CASSIA BARK/SYZGIUM AROMATICUM BUD/ROSMARINUS OFFICINALIS LEAF/THYMU…ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, ANTIPLAQUE

CITRUS KERAJI FRUIT WATERANTIPLAQUE, FRAGRANCE, HUMECTANT, ORAL CARE, SKIN CONDITIONING

DELMOPINOL HCLANTIPLAQUE, CLEANSING, ORAL CARE, SURFACTANT - CLEANSING

DEQUALINIUM CHLORIDEANTIMICROBIAL, ANTIPLAQUE, DEODORANT, ORAL CARE

ELETTARIA CARDAMOMUM FRUIT EXTRACTANTIMICROBIAL, ANTIPLAQUE

ENTEROCOCCUS FAECIUMANTIPLAQUE, SKIN CONDITIONING

ENTEROCOCCUS FAECIUM/LACTOBACILLUS/SALIX PURPUREA BARK/LEAF/STEM/WOOD/ASCORBIC …ANTI-SEBORRHEIC, ANTIPLAQUE, HUMECTANT, SKIN CONDITIONING

EUGENIA CARYOPHYLLUS BUD WATERANTIMICROBIAL, ANTIOXIDANT, ANTIPLAQUE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DOMIPHEN BROMIDE appears in the CosIng inventory

The CosIng inventory lists DOMIPHEN BROMIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DOMIPHEN BROMIDE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DOMIPHEN BROMIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DOMIPHEN BROMIDE carries the following function designation(s):

CAS 538-71-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DOMIPHEN BROMIDE

This page reproduces the CosIng inventory entry for DOMIPHEN BROMIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DOMIPHEN BROMIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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