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CAS 522-51-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 3319415/10/2010

DEQUALINIUM CHLORIDE

Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride

DEQUALINIUM CHLORIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Source mapped Inventory entry; no linked annex rule	0	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 522-51-0

CAS 522-51-0PubChem CID 10649

Dequalinium Chloride

Dequalinium chloride is an organic chloride salt that is the dichloride salt of dequalinium. It has a role as an antineoplastic agent, an antifungal agent, a mitochondrial NADH:ubiquinone reductase inhibitor and an antiseptic drug. It contains a dequalinium. — ChEBI

IUPAC name: 1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium-4-amine dichloride

Molecular formula: C30H40Cl2N4
Molecular weight: 527.6 g/mol
Exact mass: 526.2630027 Da
Topological polar surface area: 59.8 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 3
Defined stereocentres: 0

Also known as

Dequalinium DichlorideDekaminDecamineDecaminumChlorure de dequaliniumBAQD 10Dequalinii chloridumCloruro de decalinio

16 more reported names

Nordman1,1'-Decamethylenebis(4-aminoquinaldinium chloride)Dequalinio cloruroFLUOMIZINXYS8INN1I6BAQD-10GNF-Pf-5483Cloruro de decualinio1,10-Decamethylene-bis(4-aminoquinaldinium chloride)NSC-166454CHEBI:31466Quinolinium, 1,1'-(1,10-decanediyl)bis(4-amino-2-methyl-, dichlorideQuinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichlorideDequacetsdAqualinium (cation)Chloride, Dequalinium

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:31466
ChEMBL:CHEMBL121663
EPA DTXSID:DTXSID3045144

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DEQUALINIUM CHLORIDE

INCI name

DEQUALINIUM CHLORIDE

INN name

dequalinium chloride

Description

Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride

Record provenance

Inventory reference: 33194
Imported identity: DEQUALINIUM CHLORIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DEQUALINIUM CHLORIDE

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Key data

CAS

522-51-0

208-330-9

Restriction

—

Function

ANTIMICROBIAL: Preventing and/or slowing down microbial growth.
ANTIPLAQUE: Helping protect against plaque.
DEODORANT: Reducing and/or eliminating unpleasant odour. Contributing against the formation of malodour on body surfaces.
ORAL CARE: Providing cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8367 · DEQUALINIUM CHLORIDE

Ingredients with overlapping formulation functions

CINNAMOMUM CASSIA BARK/SYZGIUM AROMATICUM BUD/ROSMARINUS OFFICINALIS LEAF/THYMU…ANTI-SEBUM, ANTIMICROBIAL, ANTIOXIDANT, ANTIPLAQUE

CITRUS KERAJI FRUIT WATERANTIPLAQUE, FRAGRANCE, HUMECTANT, ORAL CARE, SKIN CONDITIONING

DELMOPINOL HCLANTIPLAQUE, CLEANSING, ORAL CARE, SURFACTANT - CLEANSING

DOMIPHEN BROMIDEANTIMICROBIAL, ANTIPLAQUE, DEODORANT, ORAL CARE

ELETTARIA CARDAMOMUM FRUIT EXTRACTANTIMICROBIAL, ANTIPLAQUE

ENTEROCOCCUS FAECIUMANTIPLAQUE, SKIN CONDITIONING

ENTEROCOCCUS FAECIUM/LACTOBACILLUS/SALIX PURPUREA BARK/LEAF/STEM/WOOD/ASCORBIC …ANTI-SEBORRHEIC, ANTIPLAQUE, HUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DEQUALINIUM CHLORIDE appears in the CosIng inventory

The CosIng inventory lists DEQUALINIUM CHLORIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DEQUALINIUM CHLORIDE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DEQUALINIUM CHLORIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DEQUALINIUM CHLORIDE carries the following function designation(s):

CAS 522-51-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DEQUALINIUM CHLORIDE

This page reproduces the CosIng inventory entry for DEQUALINIUM CHLORIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DEQUALINIUM CHLORIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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