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InventoryRef 3372310/08/2020

DMDM HYDANTOIN

1,3-bis(Hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione

DMDM HYDANTOIN is linked to 1 EU annex record on this page. Inventory note: V/33.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Positive-list entry with conditions
Open this evidence		1English and EU languages
Great BritainEvidence linked
Permitted list with conditions
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Permitted list with conditions
Open this evidence		1English
ASEANEvidence linked
Permitted list with conditions
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Restricted
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 6440-58-0
CAS 6440-58-0PubChem CID 22947

DMDM hydantoin

1,3-Dimethylol-5,5-dimethylhydantoin (DMDM hydantoin) is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. DMDM hydantoin is an organic compound belonging a class of compounds known as hydantoins. It is used in the cosmetics industry and found in products like shampoos, hair conditioners and skin care products. (L1896) — Toxin and Toxin Target Database (T3DB)

IUPAC name
1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
Molecular formula
C7H12N2O4
Molecular weight
188.18 g/mol
Exact mass
188.07970687 Da
XLogP3
-0.2
Topological polar surface area
81.1 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

DmdmhGlydant1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin1,3-Dimethylol-5,5-dimethylhydantoinDantoin-DMDMHGlycoserve-DMDMHDantoin dmdmh 55Dimethylol-5,5-dimethylhydantoin
16 more reported names
Dmdmh 552,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedioneBYR0546TOW1,3-Di(hydroxymethyl)-5,5-dimethylhydantoin1,3-DIMETHYLOL-5,5-DIMETHYL-HYDANTOINDDAC0.15%Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-RefChem:55057DDAC0.6%229-222-8938-621-2Dimethyloldimethyl hydantoindimethyloldimethylhydantoin1,3-DIHYDROXYMETHYL-5,5-DIMETHYLHYDANTOINDMDM HYDANTOIN [II]
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DMDM HYDANTOIN

INCI name

DMDM HYDANTOIN

Description

1,3-bis(Hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione

Record provenance

Inventory reference
33723
Imported identity
DMDM HYDANTOIN
Source update
10/08/2020
European Commission CosIng source notes
Annex V Restriction reference
Entry 33

DMDM HYDANTOIN

CAS: 6440-58-0
EC: 229-222-8

Key data

CAS
6440-58-0
EC
229-222-8
Restriction
V/33
Function
PRESERVATIVE
Exclusively or mainly intended to inhibit the development of micro-organisms in the cosmetic product. All authorised preservatives are substances in the positive list of Annex V to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#9564 · DMDM HYDANTOIN

The 5 markets that hold a rule for this substance do not classify it the same way.

restricted
South Korea
permitted on a positive list
European UnionGreat BritainNew ZealandASEAN

See every substance the markets disagree about

Ingredients with overlapping formulation functions

DIAZOLIDINYL UREAPRESERVATIVE
DIBROMOHEXAMIDINE ISETHIONATEPRESERVATIVE
DICHLOROBENZYL ALCOHOLANTIMICROBIAL, PRESERVATIVE
DIMETHYL OXAZOLIDINEPRESERVATIVE
EGG SHELL MEMBRANE EXTRACTPRESERVATIVE, SKIN PROTECTING
ETHYL BENZOATEFRAGRANCE, PRESERVATIVE
ETHYL LAUROYL ARGINATE HCLANTI-SEBORRHEIC, HAIR CONDITIONING, PRESERVATIVE, SKIN CONDITIONING - MISCELLANEOUS
ETHYLPARABENFRAGRANCE, PRESERVATIVE

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DMDM HYDANTOIN appears in the CosIng inventory

The CosIng inventory lists DMDM HYDANTOIN as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DMDM HYDANTOIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DMDM HYDANTOIN appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for DMDM HYDANTOIN reads: "V/33". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, DMDM HYDANTOIN carries the following function designation(s):

CAS 6440-58-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DMDM HYDANTOIN

This page combines the CosIng inventory entry for DMDM HYDANTOIN with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research DMDM HYDANTOIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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