Is DICETYL ETHER safe to use in EU cosmetics?

DICETYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 4113-12-6?

CAS 4113-12-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains DICETYL ETHER?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3325515/10/2010

DICETYL ETHER

Dihexadecyl ether

DICETYL ETHER is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 4113-12-6

CAS 4113-12-6PubChem CID 77757

Dicetyl Ether

IUPAC name: 1-hexadecoxyhexadecane

Molecular formula: C32H66O
Molecular weight: 466.9 g/mol
Exact mass: 466.511366725 Da
XLogP3: 15.6
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

Dihexadecyl etherHexadecyl etherBZ3TC4IWYYUNII-BZ3TC4IWYYNSC-77143COSMACOL ETHER 16EINECS 223-900-7NSC 77143

13 more reported names

HEXADECANE, 1-(HEXADECYLOXY)-RefChem:132998DICETYL ETHER [INCI]FDCJDKXCCYFOCV-UHFFFAOYSA-NN-HEXADECYL ETHER1-(Hexadecyloxy)hexadecaneHexadecane, 1,1'-oxybis-hexadecyletherHexadecane,1'-oxybis-1-(Hexadecyloxy)hexadecane #AS-56890CS-0452243H0075

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID30194067
PubMed:22679366
PubMed:22368393
PubMed:22321990
PubMed:22312548
PubMed:21998684
PubMed:21767850
PubMed:20957159
PubMed:20546600
PubMed:20397638
PubMed:20087463
PubMed:19433333
PubMed:19246049

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DICETYL ETHER

INCI name

DICETYL ETHER

Description

Dihexadecyl ether

Record provenance

Inventory reference: 33255
Imported identity: DICETYL ETHER
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for DICETYL ETHER

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Key data

CAS

4113-12-6

223-900-7

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8517 · DICETYL ETHER

Ingredients with overlapping formulation functions

DICAPRYLYL MALEATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

DICAPRYLYL/CAPRYL SEBACATEPLASTICISER, SKIN CONDITIONING - EMOLLIENT, SOLVENT

DICETEARETH-20 PHOSPHATESKIN CONDITIONING - EMOLLIENT; SURFACTANT - EMULSIFYING; EMULSION STABILISING

DICETYL ADIPATEFILM FORMING, PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

DICOCAMINEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

DICOCODIMETHYLAMINE DILINOLEATEHAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

DICOCOYL GLUTAMATE ESYLATESKIN CONDITIONING - EMOLLIENT; SURFACTANT - EMULSIFYING; HAIR CONDITIONING

DICOCOYL PENTAERYTHRITYL DISTEARYL CITRATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How DICETYL ETHER appears in the CosIng inventory

The CosIng inventory lists DICETYL ETHER as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DICETYL ETHER is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DICETYL ETHER is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, DICETYL ETHER carries the following function designation(s):

CAS 4113-12-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for DICETYL ETHER

This page reproduces the CosIng inventory entry for DICETYL ETHER from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research DICETYL ETHER and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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