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InventoryRef 3320715/10/2010

DIAMINOPYRIMIDINE OXIDE

2,4-Pyrimidinediamine, 3-oxide

DIAMINOPYRIMIDINE OXIDE is linked to 1 EU annex record on this page. Inventory note: III/93.

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Regulatory evidence by market

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Restricted
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Restricted
Open this evidence		1English
ASEANEvidence linked
Restricted
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaEvidence linked
Restricted
Open this evidence		1Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Restricted
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Restricted
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 74638-76-9
CAS 74638-76-9PubChem CID 10197687

Aminexil

Diaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth. — DrugBank

IUPAC name
3-hydroxy-2-iminopyrimidin-4-amine
Molecular formula
C4H6N4O
Molecular weight
126.12 g/mol
Exact mass
126.05416083 Da
XLogP3
-1.4
Topological polar surface area
85.7 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

RefChem:111997Kopexil2,4-diaminopyrimidine-3-oxide2,4-Diamino pyrimidine-3-oxideMexoryl SAG2,4-Pyrimidinediamine, 3-oxide2,6-diaminopyrimidine 1-oxide2,4-Diaminopyrimidine 3-N-oxide
10 more reported names
diaminopyrimidine oxideAC-137702,6-DIAMINOPYRIMIDIN-1-IUM-1-OLATEFT-0700705FT-0700707AMINEXIL [WHO-DD]2,4-Diaminopyrimidin-3-oxid2,4-Pyrimidinediamine 3-oxide6-Amino-2-iminopyrimidin-1(2H)-olBS-51568
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for DIAMINOPYRIMIDINE OXIDE

INCI name

DIAMINOPYRIMIDINE OXIDE

Description

2,4-Pyrimidinediamine, 3-oxide

Record provenance

Inventory reference
33207
Imported identity
DIAMINOPYRIMIDINE OXIDE
Source update
15/10/2010
European Commission CosIng source notes

Key data

CAS
74638-76-9
EC
—
Restriction
III/93
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#8412 · DIAMINOPYRIMIDINE OXIDE

Ingredients with overlapping formulation functions

DI-PEG-2 SOYAMINE/POLYDIETHYLENEGLYCOL ADIPATE/IPDI COPOLYMERFILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING
DI-PPG-3 CETETH-4 ADIPATEHAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING
DIALLYLAMMONIUM DIGLYCOL DIACETATEHAIR CONDITIONING
DIALLYLAMMONIUM SUCCINATEHAIR CONDITIONING
DIAMINOPYRIMIDINE OXIDE OXOTHIAZOLIDINECARBOXYLATEHAIR CONDITIONING, HAIR FIXING
DIAMMONIUM AMINOETHYLTHIOSUCCINATEHAIR CONDITIONING; HAIR WAVING OR STRAIGHTENING
DIANTHUS LONGICALYX SEED EXTRACTEMULSION STABILISING, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING
DIBEHENAMIDOPROPYLDIMETHYLAMINE DILINOLEATEHAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How DIAMINOPYRIMIDINE OXIDE appears in the CosIng inventory

The CosIng inventory lists DIAMINOPYRIMIDINE OXIDE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

DIAMINOPYRIMIDINE OXIDE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

DIAMINOPYRIMIDINE OXIDE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for DIAMINOPYRIMIDINE OXIDE reads: "III/93". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, DIAMINOPYRIMIDINE OXIDE carries the following function designation(s):

CAS 74638-76-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for DIAMINOPYRIMIDINE OXIDE

This page combines the CosIng inventory entry for DIAMINOPYRIMIDINE OXIDE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research DIAMINOPYRIMIDINE OXIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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