CICLOPIROX OLAMINE
6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
CICLOPIROX OLAMINE is linked to 1 EU annex record on this page. Inventory note: III/61.
Regulatory evidence by market
This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.
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| Market | Evidence status | Records | Source language |
|---|---|---|---|
| European Union | Evidence linked Restricted entry found Open this evidence | 1 | English and EU languages |
| Great Britain | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Canada | Source mapped Official source mapped; ingredient rule not imported | 0 | English and French |
| New Zealand | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| ASEAN | Source mapped Official source mapped; ingredient rule not imported | 0 | English and national languages |
| China | Source mapped Official source mapped; ingredient rule not imported | 0 | Chinese with selected English material |
| Japan | Source mapped Official source mapped; ingredient rule not imported | 0 | Japanese; official English translation available |
| South Korea | Source mapped Official source mapped; ingredient rule not imported | 0 | Korean with some English names |
| United States | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Australia | Source mapped Official source mapped; ingredient rule not imported | 0 | English |
| Brazil | Source mapped Official source mapped; ingredient rule not imported | 0 | Portuguese with INCI crosswalks |
| India | Source mapped Official source mapped; ingredient rule not imported | 0 | English and Hindi |
| Saudi Arabia | Source mapped Official source mapped; ingredient rule not imported | 0 | Arabic and English |
Chemical identity and properties
Ciclopirox Olamine
Ciclopirox Olamine is the olamine salt form of ciclopirox, a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). — NCI Thesaurus (NCIt)
- IUPAC name
- 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
- Molecular formula
- C14H24N2O3
- Molecular weight
- 268.35 g/mol
- Exact mass
- 268.17869263 Da
- Topological polar surface area
- 86.8 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEMBL:CHEMBL242580
- EPA DTXSID:DTXSID6045583
- PubMed:22232293
- PubMed:21040279
- PubMed:21039663
- PubMed:20053480
- PubMed:4517
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for CICLOPIROX OLAMINE
INCI name
CICLOPIROX OLAMINE
INN name
Ciclopirox olamine [USAN:JAN]
Description
6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Record provenance
- Inventory reference
- 32842
- Imported identity
- CICLOPIROX OLAMINE
- Source update
- 15/10/2010
Annex records for CICLOPIROX OLAMINE
Key data
- ANTI-SEBORRHEIC
- Preventing or relieving the symptoms of seborrhea and/or seborrheic dermatitis, including dandruff.
- ANTIMICROBIAL
- Preventing and/or slowing down microbial growth.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How CICLOPIROX OLAMINE appears in the CosIng inventory
The CosIng inventory lists CICLOPIROX OLAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.
CICLOPIROX OLAMINE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for CICLOPIROX OLAMINE
This page combines the CosIng inventory entry for CICLOPIROX OLAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.
Use this inventory page to research CICLOPIROX OLAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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