
Ciclopirox Olamine
Ciclopirox Olamine is the olamine salt form of ciclopirox, a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX). — NCI Thesaurus (NCIt)
- IUPAC name
- 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
- Molecular formula
- C14H24N2O3
- Molecular weight
- 268.35 g/mol
- Exact mass
- 268.17869263 Da
- Topological polar surface area
- 86.8 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEMBL:CHEMBL242580
- EPA DTXSID:DTXSID6045583
- PubMed:22232293
- PubMed:21040279
- PubMed:21039663
- PubMed:20053480
- PubMed:4517
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.