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InventoryRef 3272014/08/2020

CI 15850

Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate

CI 15850 is linked to 2 EU annex records on this page. Inventory note: IV/27 (CI 15850) III/296 (Pigment Red 57).

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Restricted entry found
Open this evidence		2English and EU languages
Great BritainSource mapped
Official source mapped; ingredient rule not imported
0English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandSource mapped
Official source mapped; ingredient rule not imported
0English
ASEANSource mapped
Official source mapped; ingredient rule not imported
0English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaSource mapped
Official source mapped; ingredient rule not imported
0English and Hindi
Saudi ArabiaSource mapped
Official source mapped; ingredient rule not imported
0Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 5858-81-1
CAS 5858-81-1PubChem CID 135487652

D & C Red No. 6

Lithol Rubine is a naphthoic acid. — ChEBI

IUPAC name
disodium;2-[(3-carboxy-2-oxidonaphthalen-1-yl)diazenyl]-5-methylbenzenesulfonate
Molecular formula
C18H12N2Na2O6S
Molecular weight
430.3 g/mol
Exact mass
430.02114584 Da
Topological polar surface area
151.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
8
Covalent units
3
Defined stereocentres
0

Also known as

Lithol rubin BLithol RubineD&C Red No. 6Siloton Rubine BVynamon Claret YIrgalite Red 4BIsol Ruby BKSegnale Red 3R
16 more reported names
Isol Ruby BKSPermanent Red 4BPlastol Rubine BCLithol Rubine BNASiloton Rubine 2BD and C Red No. 6Irgalite Rubine PBResamine Rubine BCSilotermo Carmine Gred 6Isol Bona Rubine BKPermanent Red F 6RD&c red no.6Japan Red 201Isol Bona Rubine BKSIsol Bona Rubine KBK
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CI 15850

INCI name

CI 15850

Description

Disodium 3-hydroxy-4-[(4-methyl-2-sulphonatophenyl)azo]-2-naphthoate

Record provenance

Inventory reference
32720
Imported identity
CI 15850
Source update
14/08/2020
European Commission CosIng source notes
Annex III Restriction reference
Entry 296

Pigment Red 57

CAS: 5858-81-1
EC: 227-497-9
Annex IV Restriction reference
Entry 27

CI 15850

EC: 226-109-5

Key data

CAS
5858-81-1
EC
227-497-9
Restriction
IV/27 (CI 15850) III/296 (Pigment Red 57)
Function
COLORANT
Exclusively or mainly intended to colour the cosmetic product, the body as a whole or certain parts thereof, by absorption or reflection of visible light. All authorised colorants are substances in the positive list of Annex IV to the Cosmetics Regulation 1223/2009.
HAIR DYEING
Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#6363 · CI 15850

Records sharing a CAS or EC identity

PIGMENT RED 57

Ingredients with overlapping formulation functions

CI 15580COLORANT
CI 15620COLORANT
CI 15630COLORANT
CI 15800COLORANT
CI 15865COLORANT
CI 15880COLORANT
CI 15980COLORANT
CI 15985COLORANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How CI 15850 appears in the CosIng inventory

The CosIng inventory lists CI 15850 as a cosmetic ingredient and this page links it to 2 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CI 15850 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CI 15850 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CI 15850 reads: "IV/27 (CI 15850) III/296 (Pigment Red 57)". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CI 15850 carries the following function designation(s):

CAS 5858-81-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for CI 15850

This page combines the CosIng inventory entry for CI 15850 with 2 linked Annex II–VI records from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CI 15850 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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