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CAS 5858-81-1

CAS 5858-81-1 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 5858-81-1
CAS 5858-81-1PubChem CID 135487652

D & C Red No. 6

Lithol Rubine is a naphthoic acid. — ChEBI

IUPAC name
disodium;2-[(3-carboxy-2-oxidonaphthalen-1-yl)diazenyl]-5-methylbenzenesulfonate
Molecular formula
C18H12N2Na2O6S
Molecular weight
430.3 g/mol
Exact mass
430.02114584 Da
Topological polar surface area
151.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
8
Covalent units
3
Defined stereocentres
0

Also known as

Lithol rubin BLithol RubineD&C Red No. 6Siloton Rubine BVynamon Claret YIrgalite Red 4BIsol Ruby BKSegnale Red 3R
16 more reported names
Isol Ruby BKSPermanent Red 4BPlastol Rubine BCLithol Rubine BNASiloton Rubine 2BD and C Red No. 6Irgalite Rubine PBResamine Rubine BCSilotermo Carmine Gred 6Isol Bona Rubine BKPermanent Red F 6RD&c red no.6Japan Red 201Isol Bona Rubine BKSIsol Bona Rubine KBK
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 5858-81-1

1 total
Annex
III
Entry
296

Pigment Red 57

Disodium 3-hydroxy-4-[(E)-(4- methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate

Hair dye substance in non-oxidative hair dye products

EC
227-497-9
Max concentration

How CAS 5858-81-1 is used on this site

CAS 5858-81-1 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 5858-81-1 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 5858-81-1 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.
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