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InventoryRef 3231815/10/2010

CALCIUM CHLORIDE

Calcium chloride

CALCIUM CHLORIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 10043-52-4
CAS 10043-52-4PubChem CID 5284359

Calcium Chloride

Calcium dichloride is an inorganic calcium salt, a calcium salt and an inorganic chloride. It has a role as a NMR chemical shift reference compound and a fertilizer. — ChEBI

IUPAC name
calcium dichloride
Molecular formula
CaCl2
Molecular weight
110.98 g/mol
Exact mass
109.9002962 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Covalent units
3
Defined stereocentres
0

Also known as

Calcium chloride anhydrousCaCl2DowflakeLiquidowPeladowBovikalcCalcium chloride (CaCl2)Calcium Chloride, Anhydrous
16 more reported names
Intergravin-oralesUramine MCCacl2 (anhydrous)Calcium(2+) chlorideCalcarea muriaticaCHEBI:3312INS NO.509INS-509NSC-759598E-509Calcium ChorideRefChem:5633CALCIUM CHLORIDE 10%233-140-8600-075-5Cal Plus
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:3312

calcium dichloride

Formula
Ca.2Cl
Average mass
110.984 g/mol
Monoisotopic mass
109.90030 Da
Formal charge
0
  • inorganic chloride — is a (CHEBI:36093)
  • calcium salt — is a (CHEBI:35156)
  • inorganic calcium salt — is a (CHEBI:190295)
  • bone density conservation agent — has role (CHEBI:50646)
  • anti-arrhythmia drug — has role (CHEBI:38070)
  • antineoplastic agent — has role (CHEBI:35610)
  • cardiovascular drug — has role (CHEBI:35554)
  • fertilizer — has role (CHEBI:33287)
  • NMR chemical shift reference compound — has role (CHEBI:228364)
  • bone density conservation agent — has role (CHEBI:50646)
  • anti-arrhythmia drug — has role (CHEBI:38070)
  • antineoplastic agent — has role (CHEBI:35610)
  • cardiovascular drug — has role (CHEBI:35554)
  • fertilizer — has role (CHEBI:33287)
  • NMR chemical shift reference compound — has role (CHEBI:228364)
  • inorganic chloride — is a (CHEBI:36093)
  • calcium salt — is a (CHEBI:35156)
  • inorganic calcium salt — is a (CHEBI:190295)
Additional curated names
calcium chloridecalcium dichlorideBovikalcCacl2 (anhydrous)[CaCl2]CaCl2Calcarea muriaticacalcium chloride anhydrousCalcium chloride anhydrousCalcium chloride, anhydrousCalcium chloride dihydrateCalcium chloride solutionDowflakeE-509E509INS-509INS NO.509Intergravin-oralesKalganLiquidowNSC-759598Peladow
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2024-06-06. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match5284359

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: INHALATION: move to fresh air; if discomfort persists, get medical attention.; INGESTION: give large amounts of water.; EYES: promptly flood with water and continue washing for at least 15 min.; consult an ophthalmologist.; SKIN: flush with water. (USCG, 1999) Source: CAMEO Chemicals
  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 0.3% (12 of 3505) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H319 (99.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 3505 reports by companies from 10 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 12 of 3505 reports by companies.; There are 9 notifications provided by 3493 of 3505 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P354+P338, P317, P319, P330, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Consumer Uses: Anti-freeze agent; Flavoring and nutrient; Lubricating agent; Freeze-thaw additive; Processing aids not otherwise specified; pH regulating agent; Dust suppressant; Dehydrating agent (desiccant); Soil amendments (fertilizers); Not Known or Reasonably Ascertainable; Stabilizing agent Source: EPA Chemical Data Reporting (CDR)
  • Industry Uses: Freeze-thaw additive; Lubricating agent; Binder; Anti-freeze agent; Dust suppressant; Opacifer; Surfactant (surface active agent); Processing aids not otherwise specified; Not Known or Reasonably Ascertainable; Soil amendments (fertilizers); Viscosity modifiers; Preservative; Stabilizing agent; Laboratory chemicals; Adsorbent; Processing aids, specific to petroleum production; Intermediate; Flocculating agent; Solids separation (precipitating) agent, not otherwise specified; Density modifier Source: EPA Chemical Data Reporting (CDR)
  • Sources/Uses: Used as a pavement deicer, a drying and dehydrating agent for organic liquids and gases; a drainage aid in pulp and paper processing, a sizing and finishing agent for cotton fabrics, a desiccant in hydrocarbon processing, a coal thawing agent, a component of oil well drilling muds, a set accelerator in concrete, a tire ballast; a firming agent for fruits, a fire retardant, an additive to control scaffolding in blast furnaces, a humectant in adhesives, an additive in herbicides, an additive in plastics to control particle size, a component of blood and electrolyte replacements, and other medical and veterinary uses; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Petroleum Production and Refining [Category: Industry]; Pulp and Paper Processing [Category: Industry]; Working with Glues and Adhesives [Category: Other]; Farming (Pesticides) [Category: Industry]; Cement Producing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: Both oil base and water base fracturing fluids are being used in the fracturing industry. Water base, which includes alcohol-water mixtures and low strength acids, make up the majority of treating fluids. The common chemicals added to these fluids are polymers for viscosity development, crosslinkers for viscosity enhancement, pH control chemicals, gel breakers for polymer degradation following the treatment, surfactants, clay stabilizers, alcohol, bactericides, fluid loss additives and friction reducer. /Hydraulic fracturing/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Hydraulic fracturing uses a specially blended liquid which is pumped into a well under extreme pressure causing cracks in rock formations underground. These cracks in the rock then allow oil and natural gas to flow, increasing resource production. ... Chemical Name: Calcium chloride; Chemical Purpose: Product Stabilizer; Product Function: Breaker. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For calcium chloride (USEPA/OPP Pesticide Code: 075605) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The active ingredient is no longer contained in any registered pesticide products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for CALCIUM CHLORIDE (15 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CALCIUM CHLORIDE

INCI name

CALCIUM CHLORIDE

INN name

calcium chloride

Ph. Eur. name

calcii chloridum

Description

Calcium chloride

Record provenance

Inventory reference
32318
Imported identity
CALCIUM CHLORIDE
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
10043-52-4
EC
233-140-8
Restriction
—
Function
ASTRINGENT
Contracting and/or tightening the skin.
VISCOSITY CONTROLLING
Increasing or decreasing the viscosity (thickness) of cosmetics.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#4922 · CALCIUM CHLORIDE

Ingredients with overlapping formulation functions

BOURBON EXTRACTANTIFOAMING, ASTRINGENT, FRAGRANCE
BRASSICA OLERACEA GEMMIFERA EXTRACTASTRINGENT
BRASSICA OLERACEA ITALICA EXTRACTASTRINGENT
BUPLEURUM CHINENSE ROOT EXTRACTASTRINGENT
CALCIUM LACTATEASTRINGENT, BUFFERING, KERATOLYTIC
CALCIUM SULFATE HYDRATEABRASIVE, ANTICAKING, ASTRINGENT, BINDING, BLEACHING, OPACIFYING, SKIN CONDITIONING
CAMELLIA OLEIFERA LEAF EXTRACTASTRINGENT, SKIN CONDITIONING
CAMELLIA OLEIFERA SEED EXTRACTASTRINGENT, TONIC

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How CALCIUM CHLORIDE appears in the CosIng inventory

The CosIng inventory lists CALCIUM CHLORIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CALCIUM CHLORIDE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CALCIUM CHLORIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, CALCIUM CHLORIDE carries the following function designation(s):

CAS 10043-52-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for CALCIUM CHLORIDE

This page reproduces the CosIng inventory entry for CALCIUM CHLORIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research CALCIUM CHLORIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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