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Official EU label nameGlossary entry 9109

DIOSMETIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:520-34-3
EC:208-291-8
Ingredient index records:
DIOSMETIN
Cosmetic functions: SKIN CONDITIONING

5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone

Inventory restriction note: II/260

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1 matched or reported name
DIOSMETIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name DIOSMETIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 520-34-3
CAS 520-34-3PubChem CID 5281612

Diosmetin

Diosmetin is a monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. It has a role as a tropomyosin-related kinase B receptor agonist, an antioxidant, an antineoplastic agent, a vasodilator agent, an angiogenesis inhibitor, a bone density conservation agent, an anti-inflammatory agent, an apoptosis inducer, a plant metabolite and a cardioprotective agent. It is a monomethoxyflavone, a trihydroxyflavone and a 3'-hydroxyflavonoid. It is functionally related to a luteolin. It is a conjugate acid of a diosmetin-7-olate. — ChEBI

IUPAC name
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Molecular formula
C16H12O6
Molecular weight
300.26 g/mol
Exact mass
300.06338810 Da
XLogP3
1.7
Topological polar surface area
96.2 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Luteolin 4'-methyl ether4'-MethylluteolinSalinigricoflavonolDiosmetine3',5,7-trihydroxy-4'-methoxyflavone5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one5,7,3'-Trihydroxy-4'-methoxyflavone5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone
16 more reported names
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-Flavone, 3',5,7-trihydroxy-4'-methoxy-CHEBI:4630ISAKNOX X202 WHITENING SECRET ESSENCERefChem:34944GONGJINHYANG SEOL WHITENINGWhoo Gongjinhyang Seol Whitening Jin EssenceISA KNOX WXII PLUS WHITENING REVOLUTION SERUM208-291-85,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-oneHSDB 8101KBioSS_001985KBio2_004553HY-N01255,7-dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chromen-4-one5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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