Official EU label nameGlossary entry 7607

CROCIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:42553-65-1

EC:255-881-6

Ingredient index records:

CROCIN

Cosmetic functions: ANTIOXIDANT, COLORANT

\b-D-Glucopyranose, 6-O-.beta.-D-glucopyranosyl-, 1,1'-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate] or Bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) 8,8'-diapo-ψ,ψ-carotenedioate

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1 matched or reported name

CROCIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name CROCIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 42553-65-1

CAS 42553-65-1PubChem CID 5281233

Crocin

Crocin-1 is a diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. It has a role as an antioxidant, a plant metabolite, a histological dye and a food colouring. It is a diterpenoid, a diester and a disaccharide derivative. It is functionally related to a gentiobiose and a beta-D-gentiobiosyl crocetin. — ChEBI

IUPAC name: bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate

Molecular formula: C44H64O24
Molecular weight: 977.0 g/mol
Exact mass: 976.37875290 Da
XLogP3: -2.5
Topological polar surface area: 391.0 Å²
Hydrogen-bond donors: 14
Hydrogen-bond acceptors: 24
Covalent units: 1
Defined stereocentres: 20

Also known as

CrocineCrocin 1alpha-CrocinCrocin ACrocetin bis(gentiobiosyl) estertrans-Crocetin di(beta-D-gentiobiosyl) estercrocetin di-gentiobiose ester877GWI46C2

16 more reported names

all-trans-Crocetin di-beta-D-gentiobiosyl ester8,8'-Diapo-psi,psi-carotenedioic acid, bis(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) esterbeta-D-Glucopyranose, 6-O-beta-D-glucopyranosyl-, 1,1'-((2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate)RefChem:919204254-465-1255-881-6Crocin IGardenia YellowCrocetin digentiobiose estercrocin-1.alpha.-crocincrocetin digentiobiosidetrans-crocetin bis(beta-D-gentiobiosyl) estertrans-Crocintrans-Crocin-4CCRIS 678

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External database identifiers

ChEBI:CHEBI:79068
ChEMBL:CHEMBL446785
EPA DTXSID:DTXSID7046172
PubMed:37406755

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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