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EU cosmetic ingredients, restrictions and safety
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Official EU label nameGlossary entry 7232

COENZYME A

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:85-61-0
EC:201-619-0
Ingredient index records:
COENZYME A
Cosmetic functions: SKIN CONDITIONING

Adenosine 5'-(Trihydrogen Diphosphate), 3'-(Dihydrogen Phosphate), P'-(3-Hydroxy-4-((3-((2-Mercaptoethyl)Amino)-3-Oxopropyl)Amino)-2,2-Di methyl-4-Oxobutyl) Ester, (R)-

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1 matched or reported name
COENZYME A

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name COENZYME A.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 85-61-0
CAS 85-61-0PubChem CID 87642

Coenzyme A

Coenzyme A is a thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit. It has a role as a coenzyme, a mouse metabolite and an Escherichia coli metabolite. It is a secondary carboxamide, a member of 6-aminopurines, a nucleotide derivative and a thiol. It is functionally related to a 3'-phosphate-adenosine-5'-diphosphate. It is a conjugate acid of a coenzyme A(4-). — ChEBI

IUPAC name
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] hydrogen phosphate
Molecular formula
C21H36N7O16P3S
Molecular weight
767.5 g/mol
Exact mass
767.11521025 Da
XLogP3
-5.8
Topological polar surface area
348.0 Ų
Hydrogen-bond donors
10
Hydrogen-bond acceptors
21
Covalent units
1
Defined stereocentres
5

Also known as

CoASHCoA-SHZeelHSCoACOENZYME_ASAA04E81UX3'-phosphoadenosine-(5')diphospho(4')pantatheineCHEBI:15346
16 more reported names
3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}3'-phosphoadenosine 5'-(3-((3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-((3-oxo-3-((2-sulfanylethyl)amino)propyl)amino)butyl) dihydrogen diphosphate)RefChem:127396201-619-0CoAAluzimeDepot-ZeelCoenzyme ASHCoenzym Aco-enzyme-AHS-CoAReduced CoACo-A-SHC21H36N7O16P3SCoalipLucina
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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