Official EU label nameGlossary entry 668

ACETYL HYDROXYPROLINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:33996-33-7

EC:251-780-6

Ingredient index records:

ACETYL HYDROXYPROLINE

Cosmetic functions: HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

L-Proline, 1 Acetyl-4-Hydroxy-

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1 matched or reported name

ACETYL HYDROXYPROLINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name ACETYL HYDROXYPROLINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 33996-33-7

CAS 33996-33-7PubChem CID 65784

Oxaceprol

Oxaceprol is an L-proline derivative that is L-proline substituted by acetyl and hydroxy groups at positions 1 and 4R, respectively. It is an anti-inflammatory drug used for the management of osteoarthritis. It has a role as an anti-inflammatory drug and a dermatologic drug. It is a member of acetamides, a pyrrolidinemonocarboxylic acid, a monohydroxypyrrolidine and a L-proline derivative. — ChEBI

IUPAC name: (2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid

Molecular formula: C7H11NO4
Molecular weight: 173.17 g/mol
Exact mass: 173.06880783 Da
XLogP3: -1.1
Topological polar surface area: 77.8 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 2

Also known as

Jonctumacetyl hydroxyprolineOxaceprolumN-AcetylhydroxyprolineQ0XV76B96L(-)-1-Acetyl-4-hydroxy-L-prolineRefChem:557881-Acetyl-4-hydroxy-L-proline

16 more reported names

D11AX09M01AX24251-780-6N-acetyl-4-hydroxyprolineN-Acetyl-L-hydroxyprolineAC-HYP-OHN-Acetyl-trans-4-hydroxy-L-prolineOxaceprol [INN]trans-1-Acetyl-4-hydroxy-l-prolineL-Proline, 1-acetyl-4-hydroxy-, (4R)-(4R)-1-acetyl-4-hydroxy-L-prolineOxaceprol (INN)(2s,4r)-1-acetyl-4-hydroxy-pyrrolidine-2-carboxylic acidTejuntivoCAS-33996-33-7Oxaceprolum [INN-Latin]

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External database identifiers

ChEBI:CHEBI:233149
ChEMBL:CHEMBL1407356
EPA DTXSID:DTXSID2046410

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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