Official EU label nameGlossary entry 6469
CI 77289
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 2 of 13 indexed market datasets: 1 country records and 1 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
2
Evidence gaps
11
Resolved identifiers
3
A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.
Resolved substance identity
CAS:1308-14-112001-99-9
EC:215-158-8
Ingredient index records:
CI 77289
Cosmetic functions: COLORANT
Chromic oxide hydrated; Chromium (III) hydroxide; dichromium trioxide
Inventory restriction note: IV/130
3 matched or reported names
CI 77289Chromium (III) hydroxideChromium (III) hydroxide (Pigment Green 18)
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | Conditional positive-list match | 1Open record 1 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | Review every linked record and exact conditions. |
| Great Britain GB | No local match | 0 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework. |
| Canada CA | No local match | 0 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | The Hotlist is an administrative compliance tool, not an exhaustive safety approval list. |
| New Zealand NZ | Permitted list with conditions | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | No local match | 0 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Regional annex coverage does not replace member-state implementation dates, notifications or national deviations. |
| China CN | No local match | 0 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | No local match | 0 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Korean source wording is canonical and other positive lists/notices may still apply to the formulation. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | No local match | 0 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026. |
| India IN | No local match | 0 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | The standards are separate controlled publications; absence from a locally indexed excerpt is not permission. |
| Saudi Arabia SA | No local match | 0 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply. |
No market rows match this filter.
Matching market records and conditions
New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026Exact Annex II–VI evidence
Chemical identity and properties
CAS 12001-99-9PubChem CID 22504267
C.I. Pigment Green 18
- IUPAC name
- bis(chromium(3+));tris(oxygen(2-));dihydrate
- Molecular formula
- Cr2H4O5
- Molecular weight
- 188.02 g/mol
- Exact mass
- 187.886883 Da
- Topological polar surface area
- 5.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 5
- Covalent units
- 7
- Defined stereocentres
- 0
Also known as
Chromium hydroxide greenRV8FT8XF5RChromic oxide hydratedUNII-RV8FT8XF5R11958 GREENCHROME OXIDE (HYDRATED) GREENC.I. 77289Guignet'S green
8 more reported names
RefChem:122490CHROMIUM HYDROXIDE GREEN [INCI]601-657-1chromium(3+);oxygen(2-);dihydrateHydrated chromium sesquioxideCI 77289Viridian 3BCYYGBBNBGCVXEL-UHFFFAOYSA-N
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match22504267
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: Dry Powder Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Light green finely divided powder; [MSDSonline] A brilliant emerald-green pigment called Guignet's green; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 91.7% (11 of 12) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 11 of 12 companies (only 8.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 12 reports by companies from 2 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 11 of 12 reports by companies.; There is 1 notification provided by 1 of 12 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Industry Uses: Pigment Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: A purified colorant used to color various foods, drugs, and cosmetics; [MSDSonline] Hydrated chromium oxide green is a pigment similar to Guignet's green; it is prepared differently and has less intense color; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 1308-14-1PubChem CID 14787
Chromium trihydroxide
- IUPAC name
- chromium;trihydrate
- Molecular formula
- CrH6O3
- Molecular weight
- 106.042 g/mol
- Exact mass
- 105.972199 Da
- Topological polar surface area
- 3.0 Ų
- Hydrogen-bond donors
- 3
- Hydrogen-bond acceptors
- 3
- Covalent units
- 4
- Defined stereocentres
- 0
Also known as
Chromium hydroxide (Cr(OH)3)Chromic hydroxideChromic oxide gelDichromium trioxide hydrateChromic oxide, hydrousChromium(3+) hydroxideChromic (III) hydroxideChromic acid (H3CrO3)
16 more reported names
HSDB 5796EINECS 215-158-8Chromium (III) hydroxideUNII-DX3N9U5Q97DX3N9U5Q97EC 215-158-8Chromic hydrateCHROMIUMTRIOLCHROMIUM HYDRATERefChem:576935CHROMIC(III) HYDROXIDE842-962-1CHROMIC HYDROXIDE [MI]Chromium(III) hydroxideCHROMIUM (III) HYDROXIDE N-HYDRATEChromium()Hydroxiden
External database identifiers
- EPA DTXSID:DTXSID0051651
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match14787
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: Green, gelatinous precipitate Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Large Crystals; Wet Solid; Other Solid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Blue to green solid; [ICSC] Practically insoluble in water; [Merck Index] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: BLUE-TO-GREEN POWDER OR BLACK PARTICLES. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: In an experiment performed under inert gas atmosphere, the solubility /in water/ of freshly precipitated chromium(III) hydroxide was determined from under-saturation and from over-saturation at different pH. As an amphoteric hydroxide, the solubility curve of chromium(III) hydroxide is parabolic, depending on pH. The solubility is as follows: >pH 4: moderately soluble; pH 6.8 - 11.5: insoluble; > pH 11.5 - 14 slightly soluble ... at pH 4, the solubility was about 520 mg/L; at pH 6.8 to 11.8, the solubility was about 0.005 mg/L Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Insoluble in water Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in acids and strong alkalies Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water: none Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- pH: Trivalent chromium compounds are amphoteric Source: Hazardous Substances Data Bank (HSDB)
- Carcinogen Classification: 3, not classifiable as to its carcinogenicity to humans. (L135) Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: The substance can be absorbed into the body by inhalation and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: Oral (L16) ; inhalation (L16) ; dermal (L16) Source: Toxin and Toxin Target Database (T3DB)
- Note: This chemical does not meet GHS hazard criteria for 87.4% (208 of 238) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H412 (11.8%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 238 reports by companies from 4 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 208 of 238 reports by companies.; There are 2 notifications provided by 30 of 238 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 100% (37 of 37) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 37 of 37 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 37 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 37 of 37 reports by companies.; There are 0 notifications provided by 0 of 37 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] Source: NITE-CMC
- Precautionary Statement Codes: P233, P260, P261, P271, P272, P280, P284, P302+P352, P304+P340, P321, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Health Effects: Chromium in its trivalent state is not very toxic. It may be oxidized to hexavalent chromium, a known carcinogen. Hexavalent chromium has also been shown to affect reproduction and development. (A12) Source: Toxin and Toxin Target Database (T3DB)
- Toxicity Summary: IDENTIFICATION AND USE: Chromium trihydroxide (chromic acid) is a green, gelatinous precipitate. It is used as pigment, e.g. Guignet's green; in tanning industry; as a mordant, and as catalyst for organic reactions. HUMAN EXPOSURE AND TOXICITY: Fatal case was described involving 35-year-old woman who developed severe acidosis, massive gastrointestinal hemorrhage, acute renal failure, and hepatic injury following ingestion of chromic acid (50 mL) and died 12 hours after ingestion. Postmortem liver biopsy revealed a fatty degeneration with chromium concentration 3.6 umol/g. The kidney, with chromium concentration 2.6 umol/g, had extensive necrosis and ischemic lesions. Changes in renal function among ferrochromium workers in a ferroalloy facility in China were investigated (exposed to chromium compounds such a sodium-chromate and chromium-hydroxide). The results of this study suggest that long-term exposure to chromium produces chronic renal injury, mainly involving the proximal tubule. A urinary chromium concentration of greater than 15 ug/g of creatinine can be proposed as a threshold dosage for nephrotoxicity, and gamma-glutamyl-transferase, NAG and alkaline-phosphatase are all ea Source: Hazardous Substances Data Bank (HSDB)
- Toxicity Summary: Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36) Source: Toxin and Toxin Target Database (T3DB)
- Environmental Bioconcentration: BCF values of soluble chromium(III) for bottom-feeding bivalves (oyster (Crassostrea virginica), blue mussel (Mytilus edulis), and soft shell clam (Mya arenaria)) range from 86 to 192(1). However, chromium trihydroxide is relatively insoluble between pH 6.8 and 11 (0.005 mg/L)(1). Source: Hazardous Substances Data Bank (HSDB)
- Industry Uses: Other; Catalyst Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as a pigment, mordant, catalyst, and tanning chemical; [Merck Index #2225] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Pigments, Binders, and Biocides) [Category: Paint]; Leather Tanning and Processing [Category: Industry]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: Chromium(III) hydroxide hydrates are used for the production of chromium(III) salts by reaction with the corresponding acids. /Chromium(III) hydroxide hydrates/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: As pigment; in tanning industry; as mordant; as catalyst for organic reactions. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Guignet's green. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Useful as catalyst in dehydrogenation of alcohols and paraffins, hydrogenation of olefins. /Chromic hydroxide trihydrate/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for CHROMIUM TRIHYDROXIDE (10 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Additional authoritative substance research
These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identityFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identityILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identityJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identityNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identityOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identityUS EPA CompTox CTX APIs
DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identityContinue the compliance check
1. Confirm identity
Match the supplier specification, CAS/EC identifiers and composition to this official label name. Similar wording is not proof of chemical equivalence.
2. Review restrictions
Check every exact Annex record shown above, plus CMR, nanomaterial, SCCS and later-amendment requirements that may apply.
3. Verify the formula
Evaluate concentration, product type, purity, warnings, claims and each target market before making a compliance decision.
Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
Open official Decision