Official EU label nameGlossary entry 6371

CI 16255

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 6 of 13 indexed market datasets: 7 country records and 1 EU Annex records. Every result and evidence gap is listed below.

6 markets with evidence
Markets checked
13
Markets with evidence
6
Evidence gaps
7
Resolved identifiers
4

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:2611-82-712227-64-4
EC:220-036-2235-438-3
Ingredient index records:
CI 16255
Cosmetic functions: COLORANT, HAIR DYEING

Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate

Inventory restriction note: IV/35 (CI 16255) III/192 (Acid Red 18; Acid Red 18 Aluminum Lake)

ACID RED 18
Cosmetic functions: HAIR DYEING

Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate (CI 16255)

Inventory restriction note: III/192 (Acid Red 18; Acid Red 18 Aluminum Lake) IV/35 (CI 16255)

9 matched or reported names
CI 16255ACID RED 18Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate and its insoluble barium, strontium and zirconium lakes, salts and pigmentsAcid Red 18;Acid Red 18 Aluminum LakeTrisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulfonate and its insoluble barium, strontium and zirconium lakes, salts and pigments (Acid Red 18)Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4′,6,8-trisulfonate and aluminium lake* (Acid Red 18; Acid Red 18 aluminium lake; CI 16255)Trisodium 1-(1-naphthylazo)-2- hydroxynaphthalene-4′,6,8- trisulphonate and aluminium lake Acid Red 18 CAS No 2611-82-7 Acid Red 18 Aluminum lake CAS No 12227-64-4 CI 16255Trisodium 1-(1-naphth- ylazo)-2-hydroxynaphthal- ene- -trisulphonate and 4′,6,8 15 aluminium lake ( ) Acid Red 18 (CAS 2611-82-7) Acid Red 18 Aluminum lake (CAS 12227-64-4) CI 16255and aluminium 15 lake ( )Trisodium 1-(1-naphthylazo)-2-hydroxynaphthalene-4',6,8-trisulphonate and aluminium lake (Cl 16255) (see note 17).

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

Swipe or scroll horizontally to see dataset coverage and next actions.

MarketResultRecordsDatasetMeaning / next action
European Union
EU
Conditional positive-list match1Open record 1
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
Review every linked record and exact conditions.
Great Britain
GB
Restricted2Open record 1Open record 2
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Review every linked record and exact conditions.
Canada
CA
No local match0
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
New Zealand
NZ
Restricted2Open record 1Open record 2
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
Review every linked record and exact conditions.
ASEAN
ASEAN
Restricted1Open record 1
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Review every linked record and exact conditions.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
Restricted1Open record 1
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
Review every linked record and exact conditions.
Saudi Arabia
SA
Restricted1Open record 1
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
Review every linked record and exact conditions.
No market rows match this filter.

Matching market records and conditions

European Union

Regulation (EC) 1223/2009 consolidated to 1 May 2026

Exact Annex II–VI evidence

Chemical identity and properties

PubChem 2D chemical structure for CAS 12227-64-4
CAS 12227-64-4PubChem CID 136086322

Ponceau 4R aluminum

IUPAC name
aluminum 7-hydroxy-8-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate
Molecular formula
C20H11AlN2O10S3
Molecular weight
562.5 g/mol
Exact mass
561.9391215 Da
Topological polar surface area
242.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
12
Covalent units
2
Defined stereocentres
0

Also known as

K6DSC8J075C.I. Food Red 7:1EINECS 235-438-3C.I. FOOD RED 7 ALUMINUM LAKEC.I. 16255:1RefChem:867236Aluminum, 7-hydroxy-8-(4-sulfo-1-naphthalenyl)azo-1,3-naphthalenedisulfonato(3-)-235-438-3
5 more reported names
Aluminum, (7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfonato(3-))-Aluminum, [7-hydroxy-8-[(4-sulfo-1-naphthalenyl)azo]-1,3-naphthalenedisulfonato(3-)]-UNII-K6DSC8J07511652 Dispersed RedC.I.Food Red 7:1

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match136086322

Attributed physical-property, hazard, environmental and use annotations.

  • Note: This chemical does not meet GHS hazard criteria for 100% (5 of 5) of all reports. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 5 of 5 companies. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 5 reports by companies from 1 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 5 of 5 reports by companies.; There are 0 notifications provided by 0 of 5 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 2611-82-7
CAS 2611-82-7PubChem CID 17466

C.I. Acid Red 18, trisodium salt

IUPAC name
trisodium;7-hydroxy-8-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate
Molecular formula
C20H11N2Na3O10S3
Molecular weight
604.5 g/mol
Exact mass
603.92689092 Da
Topological polar surface area
242.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
12
Covalent units
4
Defined stereocentres
0

Also known as

RefChem:1080550Ponceau 4RNew coccineAcid red 18C.I. Acid Red 18Food Red No. 102Victoria Scarlet 3RSX Purple
16 more reported names
Brilliant Scarlet 4RCoccineColacid Ponceau 4RFood Red 7Acilan Scarlet V3RAcid Brilliant Scarlet 3RCerticol Ponceau 4RSCochineal Red AAtul Acid Scarlet 3RFood Red 102Food Red Number 102C.I. Acid Red 28Edicol Supra Ponceau 4RSNeucoccinBrilliant Ponceau 3RBrilliant Scarlet 3R
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity

US EPA CompTox CTX APIs

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity

Continue the compliance check

1. Confirm identity

Match the supplier specification, CAS/EC identifiers and composition to this official label name. Similar wording is not proof of chemical equivalence.

2. Review restrictions

Check every exact Annex record shown above, plus CMR, nanomaterial, SCCS and later-amendment requirements that may apply.

3. Verify the formula

Evaluate concentration, product type, purity, warnings, claims and each target market before making a compliance decision.

Screen in a formulaOpen standalone comparison

Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision