Official EU label nameGlossary entry 6272
CHOLINE CHLORIDE
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 8 of 13 indexed market datasets: 8 country records and 0 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
8
Evidence gaps
5
Resolved identifiers
11
Resolved substance identity
CAS:67-48-1856676-23-82016-36-6507-30-24499-40-593685-90-628319-77-99008-30-497281-48-68002-43-5
EC:200-655-4
Ingredient index records:
8 matched or reported names
CHOLINE CHLORIDECholine salts and their esters, e. g. choline chloride (INN)Choline salts and their esters, e.g. choline chloride (INN)胆碱的盐类及它们的酯类,包括氯化胆 碱、菲诺贝特胆碱、胆碱水杨 酸盐、 胆碱葡萄糖酸盐、胆茶碱、硬脂酸等长 链烷烃羧酸胆碱酯; 不包括卵磷脂、 甘油磷酸胆碱、氢化溶血卵磷酸酯酰胆 碱、氢化卵磷酰 胆碱、卵磷酰胆碱类; 其他相关原料需经安全风险评估方可 确定 — Choline salts and their esters, including choline chloride （INN） （CAS No. 67-48-1）, choline fenofibrate （CAS No. 856676-23-8）, choline salicylate （CAS No. 2016-36-6）, choline gluconate （CAS No. 507-30-2）, choline theophylline （CAS No. 4499-40-5）, choline esters of stearic acid and other long alkyl chain carboxylic acids; excluding lecithin （CAS No. 93685-90-6）, glycerophosphocholine （CAS No. 28319-77-9）, hydrogenated lysophosphatidylcholine （CAS No. 9008-30-4）, hydrogenated phosphatidylcholine（CAS No. 97281-48-6）, phosphatidylcholine （CAS No. 8002-43-5）; the usage of other relevant ingredients requires safety assessment콜린염 및 에스텔(예 : 콜린클로라이드)Ésteres da Colina e da metilcolina e seus sais exceto LecitinaCholine salts and their esters, e.g. choline chloride (*) (CAS No. 67-48-1)Choline salts and their esters e.g. choline chloride (INN)
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
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| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | No local match | 0 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review. |
| Great Britain GB | Prohibited | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | No local match | 0 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | The Hotlist is an administrative compliance tool, not an exhaustive safety approval list. |
| New Zealand NZ | Prohibited | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | Prohibited | 1Open record 1 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Review every linked record and exact conditions. |
| China CN | Prohibited | 1Open record 1 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | Review every linked record and exact conditions. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | Prohibited | 1Open record 1 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Review every linked record and exact conditions. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | Prohibited | 1Open record 1 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | Review every linked record and exact conditions. |
| India IN | Prohibited | 1Open record 1 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | Review every linked record and exact conditions. |
| Saudi Arabia SA | Prohibited | 1Open record 1 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | Review every linked record and exact conditions. |
No market rows match this filter.
Matching market records and conditions
New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026ASEAN
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026South Korea
MFDS Notice 2026-19, effective 18 March 2026Brazil
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026India
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)Saudi Arabia
SFDA live prohibited/restricted lists, snapshot 30 August 2026Chemical identity and properties
CAS 2016-36-6PubChem CID 54686350
Choline Salicylate
Choline salicylate is a hydroxybenzoic acid. It is functionally related to a salicylic acid. — ChEBI
- IUPAC name
- 2-carboxyphenolate;2-hydroxyethyl(trimethyl)azanium
- Molecular formula
- C12H19NO4
- Molecular weight
- 241.28 g/mol
- Exact mass
- 241.13140809 Da
- Topological polar surface area
- 80.6 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
Choline salicylic acid saltSalicylic acid choline saltCholine, salicylate (salt)Salicilato de colinaSalicylate de cholineSalicylic acid, ion(1-), cholineCholini salicylascholine subsalicylate
16 more reported names
KD510K1IQWEthanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxybenzoic acid (1:1)(2-hydroxyethyl)trimethylazanium 2-hydroxybenzoateEthanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-hydroxybenzoate (1:1)MundasalDinnefordsRefChem:576083N02BA03217-948-8(2-Hydroxyethyl)trimethylammonium salicylateSyrap2-hydroxy-N,N,N-trimethylethanaminium 2-hydroxybenzoateArthropanActasalArtrobioneMundisal
External database identifiers
- ChEBI:CHEBI:3668
- ChEMBL:CHEMBL2104095
- EPA DTXSID:DTXSID8062103
- PubMed:16258079
- PubMed:7249509
- PubMed:3888490
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 28319-77-9PubChem CID 657272
Choline Alfoscerate
Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. — ChEBI
- IUPAC name
- [(2R)-2,3-dihydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
- Molecular formula
- C8H20NO6P
- Molecular weight
- 257.22 g/mol
- Exact mass
- 257.10282436 Da
- XLogP3
- -2.3
- Topological polar surface area
- 99.1 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 1
Also known as
SN-glycero-3-phosphocholineCholine glycerophosphateL-alpha-GlycerophosphorylcholineGlycerophosphorylcholineL-alpha-GlycerophosphocholineCholine AlphoscerateGPChoCholini glycerophosphas
16 more reported names
Cholini alfoscerasGlicerofosfato de colinaalpha-GlycerophosphorylcholineAlfoscerato de colinaGlycerophosphate de cholineAlfoscerate de cholinealpha-GlycerylphosphorylcholineGlycerol phosphorylcholineSn-3-GPCglycerol-3-phosphocholineGlycerol-3-phosphatidylcholineGliatilinCHEBI:1687060M22SGW66(2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphateL-1-glycero-3-phosphocholine
External database identifiers
- ChEBI:CHEBI:16870
- ChEBI:CHEBI:234527
- ChEBI:CHEBI:234553
- ChEBI:CHEBI:234565
- ChEBI:CHEBI:234566
- ChEMBL:CHEMBL1567463
- EPA DTXSID:DTXSID70951010
- PubMed:11744722
- PubMed:8726961
- PubMed:657272
- PubMed:5435
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 4499-40-5PubChem CID 656652
Oxtriphylline
Oxtriphylline is the choline salt form of [theophylline]. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications as the other theophyllines). It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. — DrugBank
- IUPAC name
- 1,3-dimethyl-2-oxopurin-6-olate;2-hydroxyethyl(trimethyl)azanium
- Molecular formula
- C12H21N5O3
- Molecular weight
- 283.33 g/mol
- Exact mass
- 283.16443955 Da
- Topological polar surface area
- 91.6 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
Choline theophyllinateCholinophyllinCholine theophyllineCholedylTheocolinTeofilinato de colinaTheophyllinate de cholineCholine salt with theophylline (1:1)
16 more reported names
Oxtriphylline [USP]NSC-760431Choline theophyllinate [INN]3K045XR58XOxtriphylline (USP)Choline theophylline (JAN)Choline theophyllinate (INN)CholinophyllineOxtrimethyllineSoliphyllineTeofilcolinaTheoxyllineCholegylCHOLINE THEOPHYLLINE [JAN]FiloralSabidal
External database identifiers
- ChEMBL:CHEMBL1200434
- EPA DTXSID:DTXSID20894867
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 507-30-2PubChem CID 20055440
Choline Gluconate
- IUPAC name
- 2-hydroxyethyl(trimethyl)azanium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
- Molecular formula
- C11H25NO8
- Molecular weight
- 299.32 g/mol
- Exact mass
- 299.15801676 Da
- Topological polar surface area
- 162.0 Ų
- Hydrogen-bond donors
- 6
- Hydrogen-bond acceptors
- 8
- Covalent units
- 2
- Defined stereocentres
- 4
Also known as
Choline gluconate [INN]CHOLINE D-GLUCONATEUNII-2M607MGJ8Ugluconato de colinagluconate de choline2M607MGJ8U(2-Hydroxyethyl)trimethylammonium D-gluconateacide gluconique
5 more reported names
cholini gluconascolina gluconatoRefChem:125753gluconate choline2-Hydroxy-N,N,N-trimethylethan-1-aminium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
External database identifiers
- ChEMBL:CHEMBL2104182
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 67-48-1PubChem CID 6209
Choline Chloride
Choline chloride is a quaternary ammonium salt with choline cation and chloride anion. It has a role as an animal growth promotant. It is a chloride salt and a quaternary ammonium salt. It contains a choline. — ChEBI
- IUPAC name
- 2-hydroxyethyl(trimethyl)azanium chloride
- Molecular formula
- C5H14ClNO
- Molecular weight
- 139.62 g/mol
- Exact mass
- 139.0763918 Da
- Topological polar surface area
- 20.2 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 2
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
LipotrilHepacholineParesan2-Hydroxy-N,N,N-trimethylethanaminium chloride(2-Hydroxyethyl)trimethylammonium chlorideHormoclineBiocolinaLuridin chloride
16 more reported names
Choline hydrochlorideNeocolinaBilineurin chlorideBiocolineCholinium chlorideCholine, chlorideChloride de cholineCholine chlorhydrateCholini chloridumCloruro de colinaChlorure de cholineColina cloruroTrimethyl(2-hydroxyethyl)ammonium chlorideEthanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride(beta-Hydroxyethyl)trimethylammonium chlorideNSC-402838
External database identifiers
- ChEBI:CHEBI:133341
- ChEMBL:CHEMBL282468
- EPA DTXSID:DTXSID4020325
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 856676-23-8PubChem CID 11350701
Choline Fenofibrate
Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. — NCI Thesaurus (NCIt)
- IUPAC name
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate;2-hydroxyethyl(trimethyl)azanium
- Molecular formula
- C22H28ClNO5
- Molecular weight
- 421.9 g/mol
- Exact mass
- 421.1656007 Da
- Topological polar surface area
- 86.7 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 5
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
UNII-4BMH7IZT982-Hydroxy-N,N,N-trimethylethanaminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoateFenofibrate de cholineFenofibric acid choline salt4BMH7IZT98cholini fenofibratumfenofibrato de colinaHIP0901
16 more reported names
CHOLINE FENOFIBRATE (USP-RS)2-Hydroxy-N,N,N-trimethylethanaminium 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoateCHOLINE FENOFIBRATE (MART.)CHOLINE FENOFIBRATE [MART.]CHOLINE FENOFIBRATE [USP-RS]RefChem:54817Fenofibric AcidDelayed-ReleaseC10AB11ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, SALT WITH 2-(4-(4-CHLOROBENZOYL)PHENOXY)-2-METHYLPROPANOIC ACID (1:1)TrilipixABT-335ABT 335Choline Fenofibrate;ABT-335Choline fenofibrate (USAN/INN)CHOLINE FENOFIBRATE [WHO-DD]Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate (1:1)
External database identifiers
- ChEMBL:CHEMBL1201745
- EPA DTXSID:DTXSID50234939
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 9008-30-4PubChem CID 5311264
Lysophosphatidylcholines
1-acetyl-sn-glycero-3-phosphocholine is a 1-O-acyl-sn-glycero-3-phosphocholine. — ChEBI
- IUPAC name
- [(2R)-3-acetyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
- Molecular formula
- C10H22NO7P
- Molecular weight
- 299.26 g/mol
- Exact mass
- 299.11338904 Da
- XLogP3
- -1.8
- Topological polar surface area
- 105.0 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 7
- Covalent units
- 1
- Defined stereocentres
- 1
Also known as
LysophosphatidylcholineLysophosphatidylcholine, soybeanCHEBI:60479Lysolecithins((2R)-3-acetyloxy-2-hydroxypropyl) 2-(trimethylazaniumyl)ethyl phosphate((2R)-3-acetyloxy-2-hydroxypropyl) 2-trimethylazaniumylethyl phosphate[(2R)-3-acetyloxy-2-hydroxypropyl] 2-trimethylazaniumylethyl phosphateRefChem:389099
16 more reported names
SOLEC 8160232-715-0((2R)-2-hydroxy-3-tetradecanoyloxypropyl) 2-(trimethylazaniumyl)ethyl phosphate1-acetyl-sn-glycero-3-phosphocholineUNII-CQD833204ZEINECS 232-715-0C10H22NO7PEpitope ID:1367933-sn-LysophosphatidylcholineLysophosphatidylcholines (egg)GTPL2508CHEBI:138424RYCNUMLMNKHWPZ-SNVBAGLBSA-NLysophosphatidylcholine (for injection)DA-65168L-|A-Lysophosphatidylcholine, From Egg Yolk
External database identifiers
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 93685-90-6PubChem CID 57369748
Egg yolk phosphatidylcholines
- IUPAC name
- (2-nonanoyloxy-3-octadeca-9,12-dienoyloxypropoxy)-[2-(trimethylazaniumyl)ethyl]phosphinate
- Molecular formula
- C35H66NO7P
- Molecular weight
- 643.9 g/mol
- Exact mass
- 643.45769044 Da
- XLogP3
- 9.1
- Topological polar surface area
- 102.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 7
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
VitellinYokuretopauda LPJQWAHKMIYCERGA-UHFFFAOYSA-NDA-63129
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 97281-48-6PubChem CID 65146
Distearoylphosphatidylcholine
- IUPAC name
- 2,3-di(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
- Molecular formula
- C44H88NO8P
- Molecular weight
- 790.1 g/mol
- Exact mass
- 789.62475576 Da
- XLogP3
- 15.6
- Topological polar surface area
- 111.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 8
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
1,2-Distearoyllecithin4539-70-2DioctadecanoyllecithinDistearoyl-DL-phosphatidylcholine1,2-DistearoylphosphatidylcholineDioctadecanoyl phosphatidylcholineEAG959U9714-Hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-3,5,9-trioxa-4-phosphahepta cosan-1-aminium hydroxide, inner salt, 4-oxide
16 more reported names
(2-((2,3-bis(octadecanoyloxy)propyl phosphonato)oxy)ethyl)trimethylazanium(2-{[2,3-bis(octadecanoyloxy)propyl phosphonato]oxy}ethyl)trimethylazaniumDL-DSPCRefChem:72037distearoylglycerophosphocholine1,2-distearoyllecithin, (+-)-1,2-Distearoyl-rac-glycero-3-phosphocholine816-93-32,3-Bis(stearoyloxy)propyl (2-(trimethylammonio)ethyl) phosphateLecithindistearoylDL-beta,gamma-Distearoyl-alpha-lecithinHydro Soy PC3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt,4-oxide, (7R)-1,2-DSPCStearoylLecithinUNII-EAG959U971
External database identifiers
- ChEMBL:CHEMBL113644
- EPA DTXSID:DTXSID20963380
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
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