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Official EU label nameGlossary entry 6217

CHLORINE DIOXIDE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

A missing local match is not permission, approval or proof of safety. It means no strong identity match was resolved in that indexed dataset.

Resolved substance identity

CAS:10049-04-4
Ingredient index records:
CHLORINE DIOXIDE
Cosmetic functions: ANTIMICROBIAL, DEODORANT

Chlorine Dioxide is the inorganic compound.

Open full local profile
1 matched or reported name
CHLORINE DIOXIDE

Regulatory evidence in all 13 markets

Open each matched record for its scope, concentration, conditions, warnings and official source version.

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MarketResultRecordsDatasetMeaning / next action
European Union
EU
No local match0
Complete annex dataset
Regulation (EC) 1223/2009 consolidated to 1 May 2026
No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review.
Great Britain
GB
No local match0
Complete consolidated annex dataset
GB retained Regulation 1223/2009 schedules, effective 15 August 2026
No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.
Canada
CA
No local match0
Complete Hotlist snapshot
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
New Zealand
NZ
No local match0
Complete schedules dataset
Cosmetic Products Group Standard schedules effective 1 January 2026
The searchable spreadsheet is an aid; the legal Group Standard and incorporated notices remain authoritative.
ASEAN
ASEAN
No local match0
Complete regional annex dataset
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026
Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.
China
CN
No local match0
Complete prohibited catalogues plus official-source workflow
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025
IECIC listing is not blanket approval; absence may require the new cosmetic ingredient route, and restrictions are checked separately.
Japan
JP
No local match0
Complete Standards appendices dataset
MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot
The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion.
South Korea
KR
No local match0
Complete current appendix dataset
MFDS Notice 2026-19, effective 18 March 2026
Korean source wording is canonical and other positive lists/notices may still apply to the formulation.
United States
US
No local match0
Complete enumerated federal ingredient rules
eCFR Title 21 issue date 27 August 2026
FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.
Australia
AU
No local match0
Complete cosmetic-relevant Poisons Standard subset plus official workflow
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.
Brazil
BR
No local match0
Complete prohibited dataset plus current restricted-list workflow
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026
RDC 1.030/2026 amends rather than replaces the prohibited baseline, and the second restricted-list revision was still under consultation in July 2026.
India
IN
No local match0
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Saudi Arabia
SA
No local match0
Complete official list index
SFDA live prohibited/restricted lists, snapshot 30 August 2026
No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.
No market rows match this filter.

Chemical identity and properties

PubChem 2D chemical structure for CAS 10049-04-4
CAS 10049-04-4PubChem CID 24870

Chlorine Dioxide

Molecular formula
ClO2
Molecular weight
67.45 g/mol
Exact mass
66.9586819 Da
XLogP3
1.4
Topological polar surface area
18.1 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Covalent units
1
Defined stereocentres
0

Also known as

AlcideChlorine oxide (ClO2)Chlorine(IV) oxidePuriteJoydenJoyden plusNobda disinfectantBlueMAX Pre-Post
16 more reported names
Gladiator Super DryBlueMAX Premium EURefChem:5668SKIN N CLEANVIRUS ZERO-FProVtect Hand SanitizerChlorine Dioxide(ClO2)SANI-HEALTH SanitizerPURE O2 SVIRUS KILL SANITIZERPURE O2-S FChlorine dioxide disinfectantM.C. (Morningcalm) V ZeroDMINE PENTOSE MEDI PLUS8061YMS4RMJiajia Gaseous Air Disinfectant
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:29415

dioxidochlorine(•)

Formula
ClO2
Average mass
67.451 g/mol
Monoisotopic mass
66.95868 Da
Formal charge
0
  • chlorine dioxide — is a (CHEBI:52357)
  • chlorine dioxide — is a (CHEBI:52357)
Additional curated names
dioxidochlorine(.)dioxido-lambda(5)-chloranylchlorine dioxideChlorine peroxide[ClO2](.)(OClO)(.)O2Cl(.)
Cross-references from this source
  • CAS: 10049-04-4 — NIST Chemistry WebBook
  • CAS: 10049-04-4 — KEGG COMPOUND
  • REGISTRY_NUMBER: 1265 — Gmelin
  • MANUAL_X_REF: C18368 — KEGG COMPOUND

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2014-08-03. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match24870

Attributed physical-property, hazard, environmental and use annotations.

  • Physical Description: Chlorine dioxide hydrate, frozen is an orange colored solid, appearing as a block of ice, with a faint odor of chlorine. It may only be shipped in the frozen state and then only by private or contract motor carrier. The melting point of the hydrate is around 30 °F. If it should thaw and further warm up, chlorine dioxide gas is given off. The gas is toxic by inhalation. The gas and liquid are violently decomposed by organic materials. The gas will decompose explosively at temperatures below the boiling point of water. It is used to bleach wood pulp, fats and oils; in processing flour, and for water purification. Chlorine dioxide is a yellow to reddish gas or a red-brown liquid below 52 deg. F. with an unpleasant odor similar to chlorine. Source: CAMEO Chemicals
  • Physical Description: Liquid; Gas Vapor Source: EPA Chemical Data Reporting (CDR)
  • Physical Description: Yellow to red gas or a red-brown liquid (below 52 degrees F) with an unpleasant odor similar to chlorine and nitric acid; [NIOSH] Vapor density = 2.3 (heavier than air); [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Physical Description: Liquid Source: Human Metabolome Database (HMDB)
  • Physical Description: RED-YELLOW GAS WITH PUNGENT ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
  • Physical Description: Yellow to red gas or a red-brown liquid (below 52 °F) with an unpleasant odor similar to chlorine and nitric acid. Source: Occupational Safety and Health Administration (OSHA)
  • Physical Description: Yellow to red gas or a red-brown liquid (below 52 °F) with an unpleasant odor similar to chlorine and nitric acid. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • First Aid: Excerpt from NIOSH Pocket Guide for Chlorine dioxide:; Eye: IRRIGATE IMMEDIATELY (LIQUID) - If this chemical in liquid form contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: SOAP WASH IMMEDIATELY (LIQUID) - If this chemical in liquid form contacts the skin, immediately wash the contaminated skin with soap and water. If this chemical penetrates the clothing, immediately remove the clothing, wash the skin with soap and water, and get medical attention promptly.; Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.; Swallow: MEDICAL ATTENTION IMMEDIATELY (LIQUID) - If this chemical in liquid form has been swallowed, get medical attention immediately. (NIOSH, 2024) Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately (liquid); Skin: Soap wash immediately (liquid); Breathing: Respiratory support; Swallow: Medical attention immediately (liquid) Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H270: May cause or intensify fire; oxidizer [Danger Oxidizing gases]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P220, P244, P260, P264, P271, P273, P280, P284, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P320, P321, P363, P370+P376, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P260, P264, P270, P273, P280, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H270 (29.9%): May cause or intensify fire; oxidizer [Danger Oxidizing gases]; H280 (29.2%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]; H301 (72.1%): Toxic if swallowed [Danger Acute toxicity, oral]; H314 (76.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H318 (46.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H319 (24%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330 (29.9%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H332 (15.9%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H400 (76.2%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P220, P244, P260, P261, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P320, P321, P330, P337+P317, P363, P370+P376, P391, P403, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 542 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] Source: NITE-CMC
  • Precautionary Statement Codes: P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Toxicity Summary: IDENTIFICATION AND USE: Chlorine dioxide is a yellowish-brown gas with unpleasant odor similar to chlorine and nitric acid. Its uses include bleaching cellulose, paper-pulp, flour, leather, fats and oils, textiles, and beeswax. It is also used for purification of water, taste and odor control of water, cleaning and detanning leather, in the manufacture of chloride salts, and as an oxidizing agent, bactericide, antiseptic and deodorizer. Chlorine dioxide was found to be highly effective against various microorganisms tested at very low concentrations in a minimum contact time of 30 to 60 seconds. HUMAN STUDIES: Potential symptoms of overexposure are irritation of eyes, nose, and throat, as well as coughing, wheezing, bronchitis, and pulmonary edema. Workers industrially exposed to low concentrations of the gas in air have been noted occasionally to suffer from irritation of the eyes and to see haloes about lights, but these effects have been minor compared to respiratory irritation. Bronchoscopy and biopsy revealed slight chronic bronchitis in 7 of 12 workers. Only two workers who had been exposed just prior to examination showed physical signs of respiratory effects. Workers acutel Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: Hydrogen peroxide (H2O2), chlorite, chlorate, Cl2O3, oxygen (O2), and chlorine have all been reported as intermediates or products /of chlorine dioxide breakdown/. Presumably chlorine dioxide will not persist in open basins or reservoirs, although it can remain for days in clean distribution systems. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: It is generally accepted that the predominant reaction product of chlorine dioxide in water treatment is chlorite and that chlorate and other ions are produced in minor amounts ... an approximately 50% conversion of chlorine dioxide to chlorite was reported ... /in/ water containing natural humic acids. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: Chlorine dioxide does not cause formation of trihalomethanes, does not react with ammonia, and does not cause formation of chloramines. It can ... disproportionate to chlorate and chlorite ... by raising pH to 11 or 12 ... this is not believed to be an important reaction in water undergoing treatment. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: /Products formed during oxidative treatment of water/: both oxygenated and chlorinated products may be formed, the latter being found most prominently in connection with reactions of phenolic substances. Other products that might affect health are quinones and 1,2-epoxy compounds. Source: Hazardous Substances Data Bank (HSDB)
  • Sources/Uses: Used in bleaching wood pulp (95% of use); Also used in bleaching textiles; disinfecting hospital equipment; disinfecting fruits, vegetables, and meats; and treating municipal water; [ACGIH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Pulp and Paper Processing [Category: Industry]; Textiles (Fiber & Fabric Manufacturing) [Category: Industry]; Using Disinfectants or Biocides [Category: Clean]; Sewer and Wastewater Treatment [Category: Industry]; Toxic Gas from Spilling Chemical in Water [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For chlorine dioxide (USEPA/OPP Pesticide Code: 020503) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Bleaching cellulose, paper-pulp, flour, leather, fats and oils, textiles, beeswax; purification of water; taste and odor control of water; cleaning and detanning leather; manufacture of chloride salts; oxidizing agent; bactericide, antiseptic and deodorizer. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The agricultural premises and equipment uses include the disinfection of hard surfaces and equipment (such as hatching facilities and mushroom houses) and water systems (such as chiller water and humidification water in poultry houses). Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Commercial, industrial, and medical uses include disinfection of ventilation systems, hard surfaces (e.g., floors, walls, and laboratory equipment), water systems, pulp/paper mills, and food rinses. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for Chlorine dioxide (7 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

These source-specific lookups can add hazard, toxicology, identity and assessment context. A link is a research route, not a claim that the source contains an exact record.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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Continue the compliance check

1. Confirm identity

Match the supplier specification, CAS/EC identifiers and composition to this official label name. Similar wording is not proof of chemical equivalence.

2. Review restrictions

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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