Glycol monobutyl ether acetate
- IUPAC name
- 2-butoxyethyl acetate
- Molecular formula
- C8H16O3
- Molecular weight
- 160.21 g/mol
- Exact mass
- 160.109944368 Da
- XLogP3
- 1.2
- Topological polar surface area
- 35.5 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:229414
- ChEMBL:CHEMBL2141776
- EPA DTXSID:DTXSID1026904
- PubMed:22497266
- PubMed:14726282
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 645 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 645 °F (340 °C) Source: Hazardous Substances Data Bank (HSDB)
- Autoignition Temperature: 340 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 378 °F at 760 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Boiling Point: 192 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 192 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 378 °F Source: Occupational Safety and Health Administration (OSHA)
- Boiling Point: 192 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Boiling Point: 378 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Color/Form: Colorless liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.942 at 68 °F (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
- Density: Specific gravity: 0.9422 at 20 °C/20 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 0.94 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 0.94 Source: Occupational Safety and Health Administration (OSHA)
- Density: 0.9422 @ 20°C Source: PAC Chemical Database, U.S. Department of Energy
- Density: 0.94 Source: The National Institute for Occupational Safety and Health (NIOSH)
- Flash Point: 160 °F (USCG, 1999) Source: CAMEO Chemicals
- Flash Point: 71 °C Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Flash Point: 160 °F (71 °C) (closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 71 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 71 °F Source: Occupational Safety and Health Administration (OSHA)
- Flash Point: 160 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- LogP: 1.51 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -82.3 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: Freezing point: -63.5 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -64 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -82 °F Source: Occupational Safety and Health Administration (OSHA)
- Melting Point: -63.5 °C Source: PAC Chemical Database, U.S. Department of Energy
- Melting Point: -82 °F Source: The National Institute for Occupational Safety and Health (NIOSH)
- Odor: Fruity Source: Hazardous Substances Data Bank (HSDB)
- Odor: Pleasant, sweet, fruity odor Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Ethylene glycol monobutyl ether acetate is a colorless liquid with a weak fruity odor. Floats and mixes slowly with water. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: Liquid; CBI Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless liquid with a pleasant, sweet, fruity odor; [NIOSH] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: Colorless liquid with a pleasant, sweet, fruity odor. Source: Occupational Safety and Health Administration (OSHA)
- Physical Description: Colorless liquid with a pleasant, sweet, fruity odor. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Refractive Index: Index of Refraction: 1.4200 at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 1.5 % (NIOSH, 2024) Source: CAMEO Chemicals
- Solubility: Soluble in hydrocarbons and organic solvents Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 9X10+3 mg/L at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water, g/100ml at 20 °C: 1.7 (moderate) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: 1.5% Source: The National Institute for Occupational Safety and Health (NIOSH)
- Vapor Pressure: 0.3 mmHg (NIOSH, 2024) Source: CAMEO Chemicals
- Vapor Pressure: 0.37 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 0.375 mm Hg at 20 °C Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, Pa at 20 °C: 31 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 0.3 mmHg Source: Occupational Safety and Health Administration (OSHA)
- Vapor Pressure: 0.375 [mm Hg] @20 °C Source: PAC Chemical Database, U.S. Department of Energy
- Vapor Pressure: 0.3 mmHg Source: The National Institute for Occupational Safety and Health (NIOSH)
- Exposure Routes: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Source: The National Institute for Occupational Safety and Health (NIOSH)
- First Aid: Excerpt from NIOSH Pocket Guide for 2-Butoxyethanol acetate:; Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: SOAP WASH PROMPTLY - If this chemical contacts the skin, promptly wash the contaminated skin with soap and water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with soap and water. Get medical attention promptly.; Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.; Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2024) Source: CAMEO Chemicals
- First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Soap wash promptly - If this chemical contacts the skin, promptly wash the contaminated skin with soap and water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with soap and water. Get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
- Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H332: Harmful if inhaled [Warning Acute toxicity, inhalation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P261, P271, P280, P302+P352, P304+P340, P317, P321, P362+P364, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Note: This chemical does not meet GHS hazard criteria for 0.4% (12 of 3107) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302+H312+H332 (14.7%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]; H302 (27.2%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (97.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H332 (96.6%): Harmful if inhaled [Warning Acute toxicity, inhalation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 3107 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 12 of 3107 reports by companies.; There are 11 notifications provided by 3095 of 3107 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
- Precautionary Statement Codes: P210, P260, P264, P270, P273, P280, P302+P352, P308+P316, P317, P319, P321, P362+P364, P370+P378, P403, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Target Organs: Eyes, skin, respiratory system, central nervous system, hematopoietic system, blood, kidneys, liver, lymphoid system Source: The National Institute for Occupational Safety and Health (NIOSH)
- Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)
- Environmental Bioconcentration: An estimated BCF of 4 was calculated in fish for ethylene glycol monobutyl ether acetate(SRC), using a water solubility of 9000 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 15(SRC), determined from a water solubility of 9000 mg/L(2) and a regression-derived equation(3), indicates that ethylene glycol monobutyl ether acetate is expected to have very high mobility in soil(SRC). Volatilization of ethylene glycol monobutyl ether acetate from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 5.46X10-6 atm-cu m/mole(4). Ethylene glycol monobutyl ether acetate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.375 mm Hg(5). Biodegradation of ethylene glycol monobutyl ether acetate is expected based on a screening study were 90% was degraded in 28 days(6). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 15(SRC), determined from a water solubility of 9000 mg/L(2) and a regression-derived equation(3), indicates that ethylene glycol monobutyl ether acetate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 5.46X10-6 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 9 and 70 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 4(SRC), from its water solubility(2) and a regression-derived equation(3), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Estimated hydrolysis half-lives for ethylene glycol monobutyl ether acetate are 300 and 30 days at pHs 7 and 8, respectively(6). Biodegradation of ethylene glycol monobutyl ether acetate is expected based on a screening study were 90% was degraded in 28 days(7). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethylene glycol monobutyl ether acetate, which has a vapor pressure of 0.375 mm Hg at 20 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase ethylene glycol monobutyl ether acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 18 hrs(SRC), calculated from its rate constant of 2.1X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Ethylene glycol monobutyl ether acetate contains chromophores that absorb at wavelengths >290 nm(4) and therefore may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Solvent; Other; Binder; Monomers; Diluent; Not Known or Reasonably Ascertainable; Hardener Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Cleaning agent; Not Known or Reasonably Ascertainable; Adhesion/cohesion promoter; Solvent; Binder; Other; Monomers Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Butoxyethyl Acetate Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as a solvent for lacquers, paints, enamels, resins, polymers, inks, and oils; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Solvents) [Category: Paint]; Plastic Composites Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: High-boiling solvent for nitrocellulose lacquers, epoxy resins, multicolor lacquers; film-coalescing aid for polyvinyl acetate latex. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Solvent (paints, resins) Source: Hazardous Substances Data Bank (HSDB)
- Uses: Solvent in printing inks Source: Hazardous Substances Data Bank (HSDB)
- Uses: EGBEA is primarily used as a solvent in paints. This principal use covers about 90% of its total volume. The remaining 10% are scattered within several other uses. It is used, for example, as a solvent in metal cleaning, screen printing inks and in leather processing industry or as a cleaning agent in detergents. Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE (7 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.