CAS 10101-52-7CAS 1344-21-4PubChem CID 61775
Silicic acid, zirconium(4+) salt
The Expert Panel for Cosmetic Ingredient Safety concluded that the following 24 silicate ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating, with the exception that the available data are insufficient to make a determination of safety for the use of naturally-sourced (i.e., mined) silicate ingredients in products that may be incidentally inhaled: Zirconium Silicate. — Cosmetic Ingredient Review (CIR)
- IUPAC name
- zirconium(4+) silicate
- Molecular formula
- O4SiZr
- Molecular weight
- 183.30 g/mol
- Exact mass
- 181.861284 Da
- Topological polar surface area
- 92.2 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
1344-21-4RefChem:1098530215-690-0Zirconium silicateZirconZircon (Zr(SiO4))ZirconiteZircosil
16 more reported names
Micro-Paxzirconium(4+);silicateZirconium orthosilicateZirconium(IV) silicate (1:1)Silicon zirconium oxide (SiZrO4)Silicic acid (H4SiO4), zirconium(4+) salt (1:1)Hyacinth4SY8H89134Zirconium(IV) silicateZircosil 15Standard SF 200Ultrox 500WExcelopaxZircosil 1Micro-Pax SPA-PAX 45M
External database identifiers
- EPA DTXSID:DTXSID60892246
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match61775
Attributed physical-property, hazard, environmental and use annotations.
- Physical Description: Large Crystals; CBI; Dry Powder Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Dry Powder; Other Solid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless solid; [Merck Index] Grey powder; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Colorless to greyish-white to red to brown fine powder; Odorless; [Continental Mineral Processing MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Note: This chemical does not meet GHS hazard criteria for 75.9% (189 of 249) of all reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H315 (24.1%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (24.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (24.1%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H335 (24.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 249 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 189 of 249 reports by companies.; There are 2 notifications provided by 60 of 249 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 97.8% (176 of 180) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 176 of 180 companies (only 2.2% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 180 reports by companies from 3 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 176 of 180 reports by companies.; There are 2 notifications provided by 4 of 180 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Cosmetic Ingredient Review Conclusion: The Expert Panel for Cosmetic Ingredient Safety concluded that the following 24 silicate ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating, with the exception that the available data are insufficient to make a determination of safety for the use of naturally-sourced (i.e., mined) silicate ingredients in products that may be incidentally inhaled: Zirconium Silicate. Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications; The available data are insufficient to support safety Source: Cosmetic Ingredient Review (CIR)
- Consumer Uses: Corrosion inhibitor; Filler Source: EPA Chemical Data Reporting (CDR)
- Consumer Uses: Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Binder; Other; Stabilizing agent; Filler; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Pigment Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Other; Abrasives Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Zirconium Silicate Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used in refractories, ceramics, glazes, cements, coatings for casting molds, polishing materials, gemstones, and cosmetics; Also used as a catalyst and silicone rubber stabilizer; [Merck Index] Occurs in nature as the mineral zircon; Used as a refractory, abrasive, and to make ceramic glazes and enamels; Also used in the steel and glass industries and in foundries to make molds; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Steel Producing [Category: Industry]; Abrasive Blasting [Category: Clean]; Molding and Core Making [Category: Foundry]; Glass Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Activities with risk of exposure: Ceramics making [Category: Hobbies]; Enameling [Category: Hobbies] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Sources/Uses: Naturally occurring zirconium silicate found in many different rocks and beach sand from South Carolina and Northeast Florida; [Merck Index] Used as a source of zirconium oxide, metallic zirconium, and hafnium, in abrasives, refractories, enamels, refractory porcelain, silicon rubbers, foundry cores, and as a catalyst; [Continental Mineral Processing MSDS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Abrasive Blasting [Category: Clean]; Molding and Core Making [Category: Foundry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | No exact record | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.