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Official EU label nameGlossary entry 2999

BAICALIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:21967-41-9314041-17-3
Ingredient index records:
BAICALIN
Cosmetic functions: ANTIOXIDANT, SKIN CONDITIONING

beta-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1- benzopyran-7-yl

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1 matched or reported name
BAICALIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name BAICALIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 21967-41-9
CAS 21967-41-9PubChem CID 64982

Baicalin

Baicalin is the glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis. It has a role as an antiatherosclerotic agent, an anticoronaviral agent, an EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor, a ferroptosis inhibitor, an antioxidant, an antibacterial agent, a non-steroidal anti-inflammatory drug, an antineoplastic agent, a prodrug, a neuroprotective agent, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, a plant metabolite and a cardioprotective agent. It is a glucosiduronic acid, a dihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a baicalein. It is a conjugate acid of a baicalin(1-). — ChEBI

IUPAC name
(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular formula
C21H18O11
Molecular weight
446.4 g/mol
Exact mass
446.08491139 Da
XLogP3
1.1
Topological polar surface area
183.0 Ų
Hydrogen-bond donors
6
Hydrogen-bond acceptors
11
Covalent units
1
Defined stereocentres
5

Also known as

Baicalein 7-O-glucuronideBaicalein 7-glucuronide7-D-Glucuronic acid-5,6-dihydroxyflavone5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acidCHEBI:2981347Q89U4M55,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid7-D-glucuronic acid-5,6-dihydroxy-flavone
16 more reported names
beta-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-ylRefChem:5580633-784-35,6,7-trihydroxyflavone-7-O-beta-D-glucuronate(2S,3S,4S,5R,6S)-6-((5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acidBaicalein 7-O-.beta.-D-glucuronideBaicalin 1000 microg/mL in Methanol5,6,7-trihydroxyflavone 7-O-beta-D-glucuronide(2S,3S,4S,5R,6R)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid(2S,3S,4S,5R,6S)-6-[(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acidBaicaloside(2S,3S,4S,5R,6S)-6-[(4,6-dihydroxy-5-oxo-2-phenyl-5H-chromen-7-yl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acidBaicalein-7-O-glucuronideBaicalin CRSBaicalin,(S)
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 314041-17-3
CAS 314041-17-3PubChem CID 24207712

5,6-dihydroxy-2-phenyl-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one;hydrate

IUPAC name
5,6-dihydroxy-2-phenyl-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one;hydrate
Molecular formula
C21H22O11
Molecular weight
450.4 g/mol
Exact mass
450.11621151 Da
Topological polar surface area
167.0 Ų
Hydrogen-bond donors
7
Hydrogen-bond acceptors
11
Covalent units
2
Defined stereocentres
5

Also known as

Baicalein 7-O-glucopyranoside monohydrate5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl beta-D-glucopyranoside--water (1/1)7-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropy ran-2-yloxy)]-5,6-dihydroxy-2-phenylchromen-4-one, hydrate
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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