Official EU label nameGlossary entry 29691
UROCANIC ACID
This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.
Global evidence snapshot
The resolved identity has matching regulatory evidence in 8 of 13 indexed market datasets: 8 country records and 0 EU Annex records. Every result and evidence gap is listed below.
Markets checked
13
Markets with evidence
8
Evidence gaps
5
Resolved identifiers
4
Resolved substance identity
CAS:104-98-327538-35-8
EC:203-258-4248-515-1
Ingredient index records:
UROCANIC ACID
Cosmetic functions: UV ABSORBER
2-Propenoic acid, 3-(1H-imidazol-4-yl)-
Inventory restriction note: II/418
9 matched or reported names
UROCANIC ACID3-Imidazol-4-ylacrylic acid (Urocanic acid) and its ethyl ester3-Imidazol-4-ylacrylic acid and its ethyl ester3-Imidazol-4-ylacrylic acid (urocanic acid) and its ethyl ester3-Imidazol-4-ylacrylic acid and its ethyl ester (Urocanic acid)3-咪唑-4-基丙烯酸（尿刊酸）及其乙 酯 — 3-Imidazol-4-ylacrylic acid and its ethyl ester （urocanic acid） （ CAS No. 104-98-3/ CAS No. 27538-35-8）우로카닌산, 우로카닌산에칠Ácido 3-imidazol-4-ilacrílico (ácido urocânico) e seu éster etílico3-Imidazol-4-ylacrylic acid (Urocanic acid) and its ethyl ester (urocanic acid) (CAS No. 104-98-3/27538-35-8)
Regulatory evidence in all 13 markets
Open each matched record for its scope, concentration, conditions, warnings and official source version.
Swipe or scroll horizontally to see dataset coverage and next actions.
| Market | Result | Records | Dataset | Meaning / next action |
|---|---|---|---|---|
| European Union EU | No local match | 0 | Complete annex dataset Regulation (EC) 1223/2009 consolidated to 1 May 2026 | No annex match only means that these five annexes did not return a match; CosIng identity data and other EU obligations still need review. |
| Great Britain GB | Prohibited | 1Open record 1 | Complete consolidated annex dataset GB retained Regulation 1223/2009 schedules, effective 15 August 2026 | Review every linked record and exact conditions. |
| Canada CA | Prohibited | 1Open record 1 | Complete Hotlist snapshot Health Canada Cosmetic Ingredient Hotlist, 13 August 2025 | Review every linked record and exact conditions. |
| New Zealand NZ | Prohibited | 1Open record 1 | Complete schedules dataset Cosmetic Products Group Standard schedules effective 1 January 2026 | Review every linked record and exact conditions. |
| ASEAN ASEAN | Prohibited | 1Open record 1 | Complete regional annex dataset ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026 | Review every linked record and exact conditions. |
| China CN | Prohibited | 1Open record 1 | Complete prohibited catalogues plus official-source workflow NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025 | Review every linked record and exact conditions. |
| Japan JP | No local match | 0 | Complete Standards appendices dataset MHLW Standards for Cosmetics official English source and Japanese amendments checked for the imported snapshot | The Japanese text and subsequent notices are canonical; no local match is not a product-compliance conclusion. |
| South Korea KR | Prohibited | 1Open record 1 | Complete current appendix dataset MFDS Notice 2026-19, effective 18 March 2026 | Review every linked record and exact conditions. |
| United States US | No local match | 0 | Complete enumerated federal ingredient rules eCFR Title 21 issue date 27 August 2026 | FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety. |
| Australia AU | No local match | 0 | Complete cosmetic-relevant Poisons Standard subset plus official workflow Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 | An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction. |
| Brazil BR | Prohibited | 1Open record 1 | Complete prohibited dataset plus current restricted-list workflow ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026 | Review every linked record and exact conditions. |
| India IN | Prohibited | 1Open record 1 | Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4 Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022) | Review every linked record and exact conditions. |
| Saudi Arabia SA | No local match | 0 | Complete official list index SFDA live prohibited/restricted lists, snapshot 30 August 2026 | No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply. |
No market rows match this filter.
Matching market records and conditions
Canada
Health Canada Cosmetic Ingredient Hotlist, 13 August 2025New Zealand
Cosmetic Products Group Standard schedules effective 1 January 2026ASEAN
ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026China
NMPA 2021 banned catalogues plus dynamic IECIC List I/List II system current since 2025South Korea
MFDS Notice 2026-19, effective 18 March 2026Brazil
ANVISA RDC 1.029/2026 and RDC 1.030/2026, published 15 June 2026India
Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)Chemical identity and properties
CAS 104-98-3PubChem CID 736715
Urocanic Acid
Urocanic acid is an alpha,beta-unsaturated monocarboxylic acid that is prop-2-enoic acid substituted by a 1H-imidazol-4-yl group at position 3. It is a metabolite of hidtidine. It has a role as a chromophore and a human metabolite. It is a member of imidazoles and an alpha,beta-unsaturated monocarboxylic acid. It is a conjugate acid of a urocanate. — ChEBI
- IUPAC name
- (E)-3-(1H-imidazol-5-yl)prop-2-enoic acid
- Molecular formula
- C6H6N2O2
- Molecular weight
- 138.12 g/mol
- Exact mass
- 138.042927438 Da
- XLogP3
- 0.0
- Topological polar surface area
- 66.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Urocaninic acid(2E)-3-(1H-imidazol-4-yl)prop-2-enoic acid3-(1H-Imidazol-4-yl)-2-propenoic acid2-Propenoic acid, 3-(1H-imidazol-4-yl)-G8D26XJJ3BNSC-663572-Propenoic acid, 3-(1H-imidazol-4-yl)-, (E)-CHEBI:27248
16 more reported names
Acid, UrocanicGlyoxalinylacrylic AcidAcid, GlyoxalinylacrylicRefChem:901492203-258-43-(1H-imidazol-5-yl)prop-2-enoic acidtrans-Urocanic acid4-imidazoleacrylic acid3465-72-3urocanateimidazoleacrylic acid(E)-3-(1H-imidazol-5-yl)acrylic acid5-Imidazoleacrylic acid(2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID(E)-3-(4-Imidazolyl)acrylic acid3-Imidazol-4-ylacrylic acid
External database identifiers
- ChEBI:CHEBI:27248
- ChEBI:CHEBI:30817
- ChEMBL:CHEMBL1236602
- EPA DTXSID:DTXSID5041148
- PubMed:24061166
- PubMed:15337293
- PubMed:14617103
Evidence from additional scientific databases
NIH PubChem PUG-View
Exact identifier match736715
Attributed physical-property, hazard, environmental and use annotations.
- Melting Point: 225 °C Source: DrugBank
- Melting Point: 225 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Solubility: 1500 mg/L (at 17 °C) Source: DrugBank
- Solubility: 1.5 mg/mL at 17 °C Source: Human Metabolome Database (HMDB)
- Cosmetic Ingredient Review Conclusion: The safety of this ingredient has not been documented and substantiated. The CIR Expert Panel cannot conclude whether Urocanic Acid is safe for use in cosmetic products until such time as the appropriate safety data have been obtained and evaluated. Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Ingredients for which the data are insufficient and their use in cosmetics is not supported Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Link: CIR ingredient: Urocanic Acid Source: Cosmetic Ingredient Review (CIR)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Needs review | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
CAS 27538-35-8PubChem CID 6365633
Ethyl urocanate
- IUPAC name
- ethyl (E)-3-(1H-imidazol-5-yl)prop-2-enoate
- Molecular formula
- C8H10N2O2
- Molecular weight
- 166.18 g/mol
- Exact mass
- 166.074227566 Da
- XLogP3
- 0.7
- Topological polar surface area
- 55.0 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
Parasonarl Mark II(E)-Urocanic acid ethyl esterUNII-GS4W88OP01GS4W88OP01EINECS 248-515-1Ethyl (E)-3-(1H-imidazol-4-yl)-2-propenoate2-Propenoic acid, 3-(1H-imidazol-4-yl)-, ethyl ester, (2E)-2-Propenoic acid, 3-(1H-imidazol-4-yl)-, ethyl ester, (E)-
16 more reported names
2-Propenoic acid, 3-(1H-imidazol-5-yl)-, ethyl ester, (2E)-3-(1H-Imidazol-4-yl)-2-propenoic acid, ethyl ester2-Propenoic acid, 3-(1H-imidazol-4-yl)-, ethyl esterRefChem:139070ETHYL UROCANATE [INCI](e)-3-(1h-imidazol-4-yl)-2-propenoic acid ethyl esterEthyl (2E)-3-(1H-imidazol-4-yl)prop-2-enoateethyl (2E)-3-(1H-imidazol-5-yl)prop-2-enoateEthyl 3-(1H-imidazol-4-yl)acrylateHPMLGOFBKNGJAM-ONEGZZNKSA-NEthyl (E)-3-(4-Imidazolyl)acrylateAS-48227(E)-ethyl 3-(1H-imidazol-4-yl)acrylateethyl (E)-3-(1H-imidazol-5-yl)acrylateEN300-1455951Ethyl(2E)-3-(1H-imidazol-4-yl)prop-2-enoate
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Additional authoritative substance research
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Official source and scope
Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.
Open official Decision