CAS 53188-07-1PubChem CID 40634
Trolox
Trolox is a chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures. It has a role as a ferroptosis inhibitor, an antioxidant, a radical scavenger, a neuroprotective agent and a Wnt signalling inhibitor. It is a chromanol, a monocarboxylic acid and a member of phenols. — ChEBI
- IUPAC name
- 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
- Molecular formula
- C14H18O4
- Molecular weight
- 250.29 g/mol
- Exact mass
- 250.12050905 Da
- XLogP3
- 2.8
- Topological polar surface area
- 66.8 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acidTROLOX C3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acidS18UL9710X6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acidCHEBI:82625(+--)-troloxRefChem:543360
16 more reported names
(+--)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid2h-1-benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (+--)-258-422-86-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-6-hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid( inverted exclamation markA)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromene-2-carboxylic acid(+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acidEINECS 258-422-8BRN 5052542UNII-S18UL9710XTrolox(TM)Prestwick_855(S)-Trolox?Prestwick0_000530
External database identifiers
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.