Official EU label nameGlossary entry 28951

TOCOQUINONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:7559-04-8

EC:231-450-8

Ingredient index records:

TOCOQUINONE

Cosmetic functions: ANTIOXIDANT, SKIN CONDITIONING

2,5-Cyclohexadiene-1,4-dione, 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-, [3R-(3R*, 7R*, 11R*)]-

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1 matched or reported name

TOCOQUINONE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name TOCOQUINONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7559-04-8

CAS 7559-04-8PubChem CID 2734086

Tocopherol quinone

Tocopherylquinone is an oxidized form of alpha-tocopherol with potent anticoagulant activity. Although the mechanism of action has not been fully elucidated, dietary supplementation with tocopherylquinone may lead to the inhibition of the vitamin K-dependent gamma-carboxylase (gamma-glutamyl carboxylase). This prevents the carboxylation of glutamyl residues in coagulation factor proteins and inhibits platelet aggregation and clotting. — NCI Thesaurus (NCIt)

IUPAC name: 2-[(3R,7R,11R)-3-hydroxy-3,7,11,15-tetramethylhexadecyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione

Molecular formula: C29H50O3
Molecular weight: 446.7 g/mol
Exact mass: 446.37599545 Da
XLogP3: 8.8
Topological polar surface area: 54.4 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 3

Also known as

TocopherylquinoneMetarenealpha-TocopheroquinoneZO763K43XRA0001p-Benzoquinone, 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-alpha-tocopheryl quinone2,5-Cyclohexadiene-1,4-dione, 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-, (3R-(3R*,7R*,11R*))-

16 more reported names

tocopherolquinoneAlpha-TQRefChem:8985412 (3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-1,4-benzoquinonealpha-tocopherolquinoneD-alpha-tocopherylquinoneALPHA-TOCOPHERYLQUINONEalpha-TocoquinoneTocoquinonevitamin E quinone2-((3r,7r,11r)-3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dioneATQ2-[(3R,7R,11R)-3-hydroxy-3,7,11,15-tetramethyl-hexadecyl]-3,5,6-trimethyl-1,4-benzoquinoneD-?-TocopherolquinoneA-0001D-|A-Tocopherylquinone

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External database identifiers

ChEMBL:CHEMBL1223852
EPA DTXSID:DTXSID501009892
PubMed:24130033

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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