Official EU label nameGlossary entry 2084

APIGENIN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:520-36-5

EC:208-292-3

Ingredient index records:

APIGENIN

Cosmetic functions: ANTIOXIDANT, HAIR CONDITIONING

5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

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1 matched or reported name

APIGENIN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name APIGENIN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 520-36-5

CAS 520-36-5PubChem CID 5280443

Apigenin

Apigenin is a trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells. It has a role as a metabolite and an antineoplastic agent. It is a conjugate acid of an apigenin-7-olate. — ChEBI

IUPAC name: 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

Molecular formula: C15H10O5
Molecular weight: 270.24 g/mol
Exact mass: 270.05282342 Da
XLogP3: 1.7
Topological polar surface area: 87.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneVersulinApigenol4',5,7-TrihydroxyflavoneApigenineSpigeninC.I. Natural Yellow 15,7,4'-Trihydroxyflavone

16 more reported names

Pelargidenon 14495,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-2-(p-Hydroxyphenyl)-5,7-dihydroxychromone5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyroneFLAVONE, 4',5,7-TRIHYDROXY-CHEBI:183887V515PI7F6NSC-83244UCCF-031LY-080400RefChem:6383208-292-3Chamomile oil, germanUCCF 031NSC 83244

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External database identifiers

ChEBI:CHEBI:18388
ChEMBL:CHEMBL28
EPA DTXSID:DTXSID6022391
PubMed:41049417
PubMed:40796067
PubMed:40654256
PubMed:39692359
PubMed:37730986
PubMed:37545493
PubMed:37437745
PubMed:37375837
PubMed:37353134
PubMed:37348668
PubMed:36870413
PubMed:36557792

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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