Official EU label nameGlossary entry 19039

PANTOLACTONE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:599-04-279-50-5

EC:209-963-3201-210-7

Ingredient index records:

PANTOLACTONE

Cosmetic functions: HUMECTANT, SKIN CONDITIONING

2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-

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1 matched or reported name

PANTOLACTONE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name PANTOLACTONE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 599-04-2

CAS 599-04-2PubChem CID 439368

D-Pantolactone

(R)-pantolactone is a butan-4-olide that is dihydrofuran-2(3H)-one substituted by a hydroxy group at position 3 and two methyl groups at position 4 (the R-stereoisomer). It has a role as a Saccharomyces cerevisiae metabolite. It is functionally related to a (R)-pantoic acid. — ChEBI

IUPAC name: (3R)-3-hydroxy-4,4-dimethyloxolan-2-one

Molecular formula: C6H10O3
Molecular weight: 130.14 g/mol
Exact mass: 130.062994177 Da
XLogP3: 0.5
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 1

Also known as

D-(-)-PantolactonePANTOLACTONE(R)-pantolactonepantoyl lactone(R)-Pantoyl lactone2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (3R)-(3R)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanoneJ288D7O0JS

16 more reported names

CHEBI:16719(3R)-4,4-dimethyl-3-oxidanyl-oxolan-2-oneRefChem:8584942,4-dihydroxy-3,3-dimethylbutyric acid gamma-lactone209-963-3IID733HD2M(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-oneD-(-)-Pantoyl Lactone(R)-(-)-PantolactonePantothenic lactoneUNII-J288D7O0JS(R)-(-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanonePANTOLACTONE [MI](3R)-3-hydroxy-4,4-dimethyl-tetrahydrofuran-2-onePANTOLACTONE, (-)-PANTOLACTONE, R-ISOMER

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External database identifiers

ChEBI:CHEBI:16719
ChEMBL:CHEMBL4587869
EPA DTXSID:DTXSID90881249
PubMed:20032887
PubMed:14709053
PubMed:14677931
PubMed:12662032
PubMed:12489941
PubMed:12098246
PubMed:11170253

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 79-50-5

CAS 79-50-5PubChem CID 989

(+-)-Pantolactone

DL-Pantolactone is a gamma-lactone. — ChEBI

IUPAC name: 3-hydroxy-4,4-dimethyloxolan-2-one

Molecular formula: C6H10O3
Molecular weight: 130.14 g/mol
Exact mass: 130.062994177 Da
XLogP3: 0.5
Topological polar surface area: 46.5 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

RefChem:390767DL-Pantolactone3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-oneDL-Pantoyl Lactone2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanoneD,L-Pantolactone(+/-)-pantolactone

16 more reported names

3-hydroxy-4,4-dimethyl-tetrahydrofuran-2-one(+/-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanonePantolyl lactone(D)-Pantolactone3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one (DL-Pantolactone)D-(?)-Pantolactone(rs)-pantolactoneD-(-)-Pantolyl lactoneD-(-)-Pantoic acid lactoneUNII-IID733HD2M2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-s6027alpha-hydroxy-betaD,L-Pantolactone; DL-Pantolactone; (+/-)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone; Calcium Pantothenate Impurity CNSC 5926EINECS 201-210-7

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External database identifiers

ChEBI:CHEBI:194720
ChEMBL:CHEMBL4066633
EPA DTXSID:DTXSID40861637
PubMed:22398860
PubMed:22272147
PubMed:21871058
PubMed:21699171
PubMed:21192736
PubMed:19877634
PubMed:19876606
PubMed:18684335
PubMed:18661943
PubMed:18619350
PubMed:18461583
PubMed:18386931

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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