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Official EU label nameGlossary entry 17798

OCTOPAMINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:104-14-3
EC:203-179-5
Ingredient index records:
OCTOPAMINE
Cosmetic functions: SKIN CONDITIONING

4-(2-amino-1-hydroxyethyl)phenol

Inventory restriction note: II/21

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2 matched or reported names
OCTOPAMINEoctopamine

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name OCTOPAMINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 104-14-3
CAS 104-14-3PubChem CID 4581

Octopamine

Octopamine is a member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates. It has a role as a neurotransmitter. It is a member of phenylethanolamines and a member of tyramines. It is a conjugate base of an octopaminium. — ChEBI

IUPAC name
4-(2-amino-1-hydroxyethyl)phenol
Molecular formula
C8H11NO2
Molecular weight
153.18 g/mol
Exact mass
153.078978594 Da
XLogP3
-1.1
Topological polar surface area
66.5 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

NorsynephrineNorsympatolOctopaminaoctopaminumND 501-(p-Hydroxyphenyl)-2-aminoethanolalpha-(Aminomethyl)-p-hydroxybenzyl alcoholalpha-(Aminoethyl)-4-hydroxybenzenemethanol
16 more reported names
4-OctopamineND-50Benzenemethanol, alpha-(aminomethyl)-4-hydroxy-14O50WS8JDNSC-757399CHEBI:17134para-Octopamine1-(4-Hydroxyphenyl)-2-aminoethanolOctopamine 1531RefChem:56540C01CA18203-179-5NorsympatholNordenNorphenAnalet
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External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match4581

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (50%): Harmful in contact with skin [Warning Acute toxicity, dermal] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264, P270, P280, P301+P317, P302+P352, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBINeeds review2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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