Official EU label nameGlossary entry 17575

NONOXYNOL-4

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:68412-54-49016-45-926027-38-337205-87-17311-27-527176-97-2

Ingredient index records:

NONOXYNOL-4

Cosmetic functions: SURFACTANT - EMULSIFYING

Nonoxynol-4 is the ethoxylated alkyl phenol that conforms generally to the formula, where n has an average value of 4.

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1 matched or reported name

NONOXYNOL-4

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name NONOXYNOL-4.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 27176-97-2

CAS 27176-97-2PubChem CID 176452

Tetraoxyethylene nonylphenyl ether

IUPAC name: 2-[2-[2-[2-(2-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol

Molecular formula: C23H40O5
Molecular weight: 396.6 g/mol
Exact mass: 396.28757437 Da
XLogP3: 5.4
Topological polar surface area: 57.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

Tetraethylene glycol monononylphenol etheralpha-Nonylphenyl-omega-hydroxytetrakis(oxyethylene)Ethanol, 2-(2-(2-(2-(nonylphenoxy)ethoxy)ethoxy)ethoxy)-RefChem:3842554-Nonylphenol tetraethoxylate, mixture of nonylisomers2-(2-{2-[2-(2-Nonylphenoxy)ethoxy]ethoxy}ethoxy)ethan-1-ol

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External database identifiers

EPA DTXSID:DTXSID60181647

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 37205-87-1

CAS 37205-87-1PubChem CID 92035818

Nonoxynol-1

The CIR Expert Panel concluded that the following 27 Nonoxynols listed below are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating..Nonoxynol-1... — Cosmetic Ingredient Review (CIR)

IUPAC name: 1-ethoxy-4-(7-methyloctyl)benzene

Molecular formula: C17H28O
Molecular weight: 248.4 g/mol
Exact mass: 248.214015512 Da
XLogP3: 6.6
Topological polar surface area: 9.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

Marlophen NP 6Marlophen NP 8Marlophen NP 10Marlophen NP 12Neonol AF 9Neonol AF 10Neonol AF9 10ANeonol AF9 12A

16 more reported names

Neonol AF 9-5Neonol AF 9-9Neonol AF 9-10Neonol AF 9-22Neonol AF 9-25Neonol AF 9-60MAF 12Nonoxynol5Nonoxynol6Nonoxynol10Nonoxynol11Nonoxynol12Nonoxynol20Nonoxynol23Nonoxynol35Nonoxynol40

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Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7311-27-5

CAS 7311-27-5PubChem CID 81745

Ethanol, 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]-

IUPAC name: 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol

Molecular formula: C23H40O5
Molecular weight: 396.6 g/mol
Exact mass: 396.28757437 Da
XLogP3: 5.4
Topological polar surface area: 57.2 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

Tetraethylene glycol mono(p-nonylphenyl) ether2-(2-(2-(2-(4-Nonylphenoxy)ethoxy)ethoxy)ethoxy)ethanolEINECS 230-770-5Ethanol, 2-(2-(2-(2-(4-nonylphenoxy)ethoxy)ethoxy)ethoxy)-Ethanol, 2-(2-(2-(2-(p-nonylphenoxy)ethoxy)ethoxy)ethoxy)-RefChem:200832Ethanol, 2-2-2-2-(4-nonylphenoxy)ethoxyethoxyethoxy-4-nonylphenol tetraethoxylate

10 more reported names

Nonoxynol-42-(2-{2-[2-(4-nonylphenoxy)ethoxy]ethoxy}ethoxy)ethan-1-ol2-(2-(2-(2-(4-Nonylphenoxy)ethoxy)ethoxy)ethoxy)ethan-1-olNPEO4Nonylphenol-4-ethoxylatePEG-4 Nonyl phenyl ether4-n-Nonylphenol tetraethoxylateUTXPMECBRCEYCI-UHFFFAOYSA-NDB-2868342-[2-[2-[2-(4-Nonylphenoxy)ethoxy]ethoxy]ethoxy] ethanol

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External database identifiers

ChEMBL:CHEMBL2107128
EPA DTXSID:DTXSID0064624

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 9016-45-9

CAS 9016-45-9PubChem CID 24773

4-Nonylphenol diethoxylate

IUPAC name: 2-[2-(4-nonylphenoxy)ethoxy]ethanol

Molecular formula: C19H32O3
Molecular weight: 308.5 g/mol
Exact mass: 308.23514488 Da
XLogP3: 5.6
Topological polar surface area: 38.7 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Nonoxynol-2U4A966MO25RefChem:1071320243-816-44-Nonyl Phenol Diethoxylate2-(2-(4-Nonylphenoxy)ethoxy)ethanol2-[2-(4-nonylphenoxy)ethoxy]ethan-1-olEthanol, 2-(2-(4-nonylphenoxy)ethoxy)-

16 more reported names

Polyoxyethylene (12) nonylphenyl etherEthanol, 2-[2-(4-nonylphenoxy)ethoxy]-DSSTox_CID_16588DSSTox_RID_79288DSSTox_GSID_36588Adekatol NPNonylphenol Ethoxylate(Tergitol NP-40)EON 2CAS-26027-38-3Igepal CO-210NonoxinolumUNII-U4A966MO25NPEOxEINECS 243-816-4NP-40 SubstituteNPEO2

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External database identifiers

ChEMBL:CHEMBL194034
EPA DTXSID:DTXSID9058600

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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