Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
Official EU label nameGlossary entry 17351

NEOTAME

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:165450-17-9
Ingredient index records:
NEOTAME
Cosmetic functions: FRAGRANCE

L-Phenylalanine, N-(3,3-dimethylbutyl)-L-alpha-aspartyl-, 2-methyl ester

Open full local profile
1 matched or reported name
NEOTAME

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name NEOTAME.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sourcesSearch every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 165450-17-9
CAS 165450-17-9PubChem CID 9810996

Neotame

Neotame is a dipeptide composed of N-(3,3-dimethylbutyl)-L-aspartic acid and methyl L-phenylalanate units joined by a peptide linkage. It has a role as a xenobiotic, a sweetening agent and an environmental contaminant. — ChEBI

IUPAC name
(3S)-3-(3,3-dimethylbutylamino)-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
Molecular formula
C20H30N2O5
Molecular weight
378.5 g/mol
Exact mass
378.21547206 Da
XLogP3
-0.1
Topological polar surface area
105.0 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
2

Also known as

N-(N-(3,3-dimethylbutyl)-L-alpha-aspartyl)-L-phenylalanine 1-methyl esterVJ597D52EXINS NO.961INS-961CHEBI:83503NC-00723E 961E-961
16 more reported names
RefChem:1654093-((3,3-dimethylbutyl)amino)-3-((1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl)propanoic acid(S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acidNeotame [NF]NEOTAME [FHFI]NEOTAME [USP-RS]L-Phenylalanine, N-(3,3-dimethylbutyl)-L-alpha-aspartyl-, 2-methyl esterCS-W011769(3S)-3-[(3,3-dimethylbutyl)amino]-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acidGS-3213methyl N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalaninateNeutame.UNII-VJ597D52EXNC 00723HSDB 7965N-boc amino alc
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

Take this record further

Screen in a formulaOpen standalone comparison

Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision