Official EU label nameGlossary entry 15747

MADECASSIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

Markets checked

Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:18449-41-7

Ingredient index records:

MADECASSIC ACID

Cosmetic functions: SKIN CONDITIONING

Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-

Open full local profile

1 matched or reported name

MADECASSIC ACID

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name MADECASSIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

Check the markets and their sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 18449-41-7

CAS 18449-41-7PubChem CID 73412

Madecassic Acid

Madecassic acid is a pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3, 6 and 23 (the 2alpha,3beta,6beta stereoisomer). It has a role as an antioxidant, an antibacterial agent, a hypoglycemic agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite. It is a monocarboxylic acid, a pentacyclic triterpenoid and a tetrol. It is a conjugate acid of a madecassate. It derives from a hydride of an ursane. — ChEBI

IUPAC name: (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

Molecular formula: C30H48O6
Molecular weight: 504.7 g/mol
Exact mass: 504.34508925 Da
XLogP3: 4.4
Topological polar surface area: 118.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 6
Covalent units: 1
Defined stereocentres: 13

Also known as

Brahmic acidORISTRACT MDACHEBI:73058M7O1N24J82Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2alpha,3beta,4alpha,6beta)-2alpha,3beta,6beta,23-Tetrahydroxyurs-12-en-28-oic Acid(2alpha,3beta,6beta)-2,3,6,23-tetrahydroxyurs-12-en-28-oic acidNSC-88135

16 more reported names

RefChem:41931Callicos CellAwake Mask madecassol606-031-16beta-hydroxyasiatic acidUNII-M7O1N24J82Madecassic acid (Standard)Madecassic Acid (97%)SR-05000002181(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acidPRAUVHZJPXOEIF-AOLYGAPISA-NNSC 88135HY-N0569RMADECASSIC ACID [WHO-DD]6.BETA.-HYDROXYASIATIC ACIDHY-N0569AC-6055

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:73058
ChEMBL:CHEMBL481854
EPA DTXSID:DTXSID70939838
PubMed:38527925
PubMed:11408205

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

Take this record further

Screen in a formula Open standalone comparison

Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

Open official Decision