CAS 3902-71-4PubChem CID 5585
Trimethylpsoralen
Trioxsalen is 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phototherapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermis. It has a role as a photosensitizing agent and a dermatologic drug.
— ChEBI
- IUPAC name
- 2,5,9-trimethylfuro[3,2-g]chromen-7-one
- Molecular formula
- C14H12O3
- Molecular weight
- 228.24 g/mol
- Exact mass
- 228.078644241 Da
- XLogP3
- 3.0
- Topological polar surface area
- 39.4 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 3
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
trioxsalenTrioxysalen4,5',8-TrimethylpsoralenTrioxisalenoTrioxysalene2',4,8-TrimethylpsoralenTrioxysalenumTmp (psoralen)
16 more reported names
NSC 710477H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-Y6UY8OV51T2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one7H-Furo(3,2-g)(1)benzopyran-7-one, 2,5,9-trimethyl-2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-oneCHEBI:283296-hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactoneTrioxisalenum2,5,9-trimethylfuro(3,2-g)chromen-7-one4,7,9-trimethyl-2H-furo(3,2-g)chromen-2-one4,7,9-trimethyl-2H-furo[3,2-g]chromen-2-onetrioxisaleneRefChem:581762,5,9-Trimethyl-7H-furo(3,2-g)benzopyran-7-oneD05AD01
External database identifiers
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
