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EU cosmetic ingredients, restrictions and safety
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Official EU label nameGlossary entry 14866

LAPACHOL

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
0

Resolved substance identity

Ingredient index records:
LAPACHOL
Cosmetic functions: ANTIOXIDANT, SKIN PROTECTING

Lapachol

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1 matched or reported name
LAPACHOL

Each compound below is connected through an exact CosIng ingredient-name match and an exact PubChem synonym match. It is not inferred from a partial or similar name.

Npc216413

Exact match
IUPAC name
4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-dione
Molecular formula
C15H14O3
Molecular weight
242.27 g/mol
InChIKey
CWPGNVFCJOPXFB-UHFFFAOYSA-N
PubChem CID
3884

Lapachol is a hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone substituted by hydroxy and 3-methylbut-2-en-1-yl groups at positions 2 and 3, respectively. It is a natural compound that exhibits antibacterial and anticancer properties, first isolated in 1882 from the bark of Tabebuia avellanedae. It has a role as an antibacterial agent, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a hydroxy-1,4-naphthoquinone and an olefinic compound.

Open local ingredient profileOpen PubChem evidence

Exact CosIng INCI name equals a PubChem synonym · Checked 2026-08-31

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name LAPACHOL.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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