Official EU label nameGlossary entry 13425

HYDROXYTRYPTOPHAN

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Markets with evidence

Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:56-69-9

EC:200-284-8

Ingredient index records:

HYDROXYTRYPTOPHAN

Cosmetic functions: SKIN CONDITIONING

5-Hydroxytryptophan

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1 matched or reported name

HYDROXYTRYPTOPHAN

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name HYDROXYTRYPTOPHAN.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 56-69-9

CAS 56-69-9PubChem CID 144

(+-)-5-Hydroxytryptophan

5-hydroxytryptophan is a tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5. It has a role as a neurotransmitter and a human metabolite. — ChEBI

IUPAC name: 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Molecular formula: C11H12N2O3
Molecular weight: 220.22 g/mol
Exact mass: 220.08479225 Da
XLogP3: -1.2
Topological polar surface area: 99.3 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

5-hydroxytryptophan114-03-45-HTPDL-5-HTPTryptophan, 5-hydroxy-9181P3OI6NCHEBI:281715 Hydroxytryptophan

16 more reported names

2-azaniumyl-3-(5-hydroxy-1H-indol-3-yl)propanoateTryptophan, 5 Hydroxy5-hydroxytryptophan DL-RefChem:905501200-284-8Oxytryptophan5-Hydroxy-DL-tryptophanDL-5-HydroxytryptophanDL-HydroxytryptophanH-DL-Trp(5-OH)-OHD,L-5-hydroxytryptophan5-Hydroxytryptophan DL-form5-hydroxy tryptophanNSC-925235-HTP/5-Hydroxytryptophan(+/-)-5-Hydroxytryptophan

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External database identifiers

ChEBI:CHEBI:28171
ChEMBL:CHEMBL162789
EPA DTXSID:DTXSID50859863
PubMed:23112413
PubMed:23000748
PubMed:22954188
PubMed:22897877
PubMed:22842218
PubMed:22778841
PubMed:22776496
PubMed:22729819
PubMed:22722514
PubMed:22713342
PubMed:22691588
PubMed:22689620

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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