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Official EU label nameGlossary entry 13215

HYDROXYCORTISONE SUCCINATE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
2

Resolved substance identity

CAS:2203-97-6
EC:218-612-3
Ingredient index records:
HYDROXYCORTISONE SUCCINATE
Cosmetic functions: SKIN CONDITIONING

Pregn-4-ene-3,20-dione, 21-(3-Carboxy-1-Oxopropoxy)-11,17-Dihydroxy-, (11βeta)-

Inventory restriction note: II/300

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1 matched or reported name
HYDROXYCORTISONE SUCCINATE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name HYDROXYCORTISONE SUCCINATE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 2203-97-6
CAS 2203-97-6PubChem CID 16623

Hydrocortisone Succinate

Hydrocortisone succinate is a derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone). It is a hemisuccinate, a tertiary alpha-hydroxy ketone and a dicarboxylic acid monoester. It is functionally related to a cortisol. — ChEBI

IUPAC name
4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
Molecular formula
C25H34O8
Molecular weight
462.5 g/mol
Exact mass
462.22536804 Da
XLogP3
1.8
Topological polar surface area
138.0 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
8
Covalent units
1
Defined stereocentres
7

Also known as

Cortisol succinateHydrocortisone hydrogen succinateHydrocortisone hemisuccinate anhydrousNSC-7576ORISTAR HCSHSHydroxycortisone succinateIHV1VP592VCHEBI:31677
16 more reported names
Cortisol 21-(hydrogen succinate)11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione 21-succinate11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-(hydrogensuccinate)RefChem:78901311beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-(hydrogen succinate)pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11beta)-218-612-3Hydrocortisone 21-hemisuccinateCortisol 21-hemisuccinateHydrocortisone succinate [JAN]SolucortefArcocortIntracortOralsoneCorlanPregn-4-ene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)-
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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