Official EU label nameGlossary entry 12094

HISTIDINE HCl

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:645-35-25934-29-2

EC:211-438-9

Ingredient index records:

HISTIDINE HCL

Cosmetic functions: HAIR CONDITIONING, SKIN CONDITIONING

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1 matched or reported name

HISTIDINE HCL

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name HISTIDINE HCl.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 5934-29-2

CAS 5934-29-2PubChem CID 165377

Histidine Monohydrochloride Monohydrate

IUPAC name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrate;hydrochloride

Molecular formula: C6H12ClN3O3
Molecular weight: 209.63 g/mol
Exact mass: 209.0567189 Da
Topological polar surface area: 93.0 Å²
Hydrogen-bond donors: 5
Hydrogen-bond acceptors: 5
Covalent units: 3
Defined stereocentres: 1

Also known as

L-Histidine Hydrochloride MonohydrateL-Histidine hydrochloride hydrateL-Histidine monohydrochloride monohydrateL-Histidine HCl hydrateL-Histidine, monohydrochloride, monohydrateHistidine hydrochloride hydrateHistidine, monohydrochloride, monohydrate, L-histidine hydrochloride monohydrate

16 more reported names

L-Histidine hydrochloride hydrate (JP17)L-HISTIDINE HYDROCHLORIDE HYDRATE [JAN]HISTIDINE, L-, HYDROCHLORIDE MONOHYDRATEHISTIDINE, L-, MONOHYDROCHLORIDE MONOHYDRATEHISTIDINE MONOHYDROCHLORIDE MONOHYDRATE, (-)-L-HISTIDINE, HYDROCHLORIDE, HYDRATE (1:1:1)HISTIDINE HYDROCHLORIDE MONOHYDRATE [EP MONOGRAPH]L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE [USP-RS]HISTIDINE HYDROCHLORIDE MONOHYDRATE (EP MONOGRAPH)L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE (USP-RS)RefChem:788396(Former JAN: L-Histidine Monohydrochloride)L-HISTIDINE HYDROCHLORIDE HYDRATE L-HISTIDINE MONOHYDROCHLORIDEL-HISTIDINE HYDROCHLORIDE HYDRATE L-HISTIDINE MONOHYDROCHLORIDE [JAN](2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid monohydrochloride monohydrate611-821-4

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External database identifiers

EPA DTXSID:DTXSID00208089
PubMed:9103

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 645-35-2

CAS 645-35-2PubChem CID 66091

Histidine Monohydrochloride

IUPAC name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrochloride

Molecular formula: C6H10ClN3O2
Molecular weight: 191.61 g/mol
Exact mass: 191.0461543 Da
Topological polar surface area: 92.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 2
Defined stereocentres: 1

Also known as

L-Histidine hydrochloride1007-42-7Histidine hydrochlorideHistidine HClL-Histidine, monohydrochlorideL-Histidine monohydrochloride(-)-Histidine monohydrochlorideL-Histidine hydrochloride (VAN)

16 more reported names

Histidine hydrochloride, L-Histidine hydrochloride (VAN)L-Histidine, hydrochloride (1:1)EINECS 211-438-9Histidine monohydrochloride, L-(+)-NSC 257867PHOTONYLHistidine monohydrochloride [NF]AI3-184731D5Q932XM6EINECS 213-754-2NSC-257867DL-Histidine, hydrochlorideL-Histidine, monohydrochloride, hydrateSUNACTYL LS 9610OSMHYDRAN LS 8453

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External database identifiers

ChEMBL:CHEMBL1256578
EPA DTXSID:DTXSID3020700
PubMed:5779

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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