Official EU label nameGlossary entry 12092

HISTIDINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:71-00-1

EC:200-745-3

Ingredient index records:

HISTIDINE

Cosmetic functions: ANTISTATIC, HUMECTANT, SKIN CONDITIONING

Histidine

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2 matched or reported names

HISTIDINEhistidine

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name HISTIDINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 71-00-1

CAS 71-00-1PubChem CID 6274

L-Histidine

L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a histidine and a proteinogenic amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion. — ChEBI

IUPAC name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid

Molecular formula: C6H9N3O2
Molecular weight: 155.15 g/mol
Exact mass: 155.069476538 Da
XLogP3: -3.2
Topological polar surface area: 92.0 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

histidineglyoxaline-5-alanineL-(-)-HistidinehistidinaIstidinaHISTIDINE, L-L-Histidin(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

16 more reported names

(S)-4-(2-Amino-2-carboxyethyl)imidazoleFEMA No. 3694L-His(S)-alpha-amino-1H-imidazole-4-propanoic acidHistidinum4-(2-Amino-2-carboxyethyl)imidazole(S)-2-Amino-3-(4-imidazolyl)propionsaeure(S)-alpha-Amino-1H-imidazole-4-propionic acid(S)-a-Amino-1H-imidazole-4-propanoic acidalpha-Amino-4(or 5)-imidazolepropionic acid1H-Imidazole-4-propanoic acid, alpha-amino-, (S)-4QD397987ENSC-137773CHEBI:15971(2S)-2-amino-3-(imidazol-4-yl)propanoic acid(S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

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External database identifiers

ChEBI:CHEBI:15971
ChEMBL:CHEMBL17962
EPA DTXSID:DTXSID9023126
PubMed:39172838
PubMed:38971454
PubMed:35151785
PubMed:31254495
PubMed:29968805
PubMed:27845049
PubMed:27543355
PubMed:25238095
PubMed:23124343
PubMed:23122502
PubMed:23109729
PubMed:23105881

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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