1-Hexanol
- IUPAC name
- hexan-1-ol
- Molecular formula
- C6H14O
- Molecular weight
- 102.17 g/mol
- Exact mass
- 102.104465066 Da
- XLogP3
- 2.0
- Topological polar surface area
- 20.2 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 1
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:87393
- ChEMBL:CHEMBL14085
- EPA DTXSID:DTXSID8021931
- PubMed:23125701
- PubMed:23107699
- PubMed:23021801
- PubMed:22970999
- PubMed:22965714
- PubMed:22928292
- PubMed:22905387
- PubMed:22819734
- PubMed:22818888
- PubMed:22796674
- PubMed:22730107
- PubMed:22718560
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 580 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 290 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 314.8 °F at 760 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Boiling Point: 157 °C at 760 mm Hg Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: Boiling points at various pressures. [Table#1649] Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 156.00 to 157.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 157 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 157 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Boiling Point: 157.2 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: Colorless liquid Source: Hazardous Substances Data Bank (HSDB)
- Density: 0.85 at 68 °F (USCG, 1999) - Less dense than water; will float Source: CAMEO Chemicals
- Density: 0.8153 at 25 °C/4 °C; 0.8082 at 35 °C/4 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: Bulk density = 6.8 lb/gal Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 0.82 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 0.816-0.821 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 0.8204 @ 20°C Source: PAC Chemical Database, U.S. Department of Energy
- Flash Point: 145 °F (USCG, 1999) Source: CAMEO Chemicals
- Flash Point: 73.9 °C (Open cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 58.4 °C (Closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 145 °F (63 °C) (Closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 63 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- LogP: log Kow = 2.03 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 2.03 Source: Human Metabolome Database (HMDB)
- LogP: 2.03 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -48.3 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: -44.6 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -44.6 °C Source: Human Metabolome Database (HMDB)
- Melting Point: -44.6 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -46.7 °C Source: PAC Chemical Database, U.S. Department of Energy
- Odor: Characteristic; sweet alcohol; pleasant Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Hexanols appears as a clear colorless liquid mixture of isomeric six-carbon alcohols with similar chemical properties. Vapors are heavier than air. Used to make pharmaceuticals and as a solvent. Source: CAMEO Chemicals
- Physical Description: N-hexanol appears as a clear colorless liquid. Flash point 149 °F. Less dense than water and insoluble in water. Vapors heavier than air. Source: CAMEO Chemicals
- Physical Description: Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless liquid with a fruity odor; [CHEMINFO] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: colourless, mobile liquid/mild, sweet, green Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: Index of refraction = 1.4162 at 25 °C/4 °C Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: 1.415-1.420 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: Sol in ethanol, acetone, chloroform; miscible with ether, benzene; slightly soluble in carbon tetrachloride Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 5,900 mg/L at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water, g/100ml at 20 °C: 0.59 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: miscible with alcohol, ether, 1 ml in 175 ml water Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 38.78 mmHg (USCG, 1999) Source: CAMEO Chemicals
- Vapor Pressure: 0.92 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: 0.928 mm Hg at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, kPa at 25 °C: 0.124 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 1 [mm Hg] @24.4 °C Source: PAC Chemical Database, U.S. Department of Energy
- Viscosity: 0.592 cP at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: The substance can be absorbed into the body by inhalation and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- First Aid: Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:; Refer to the "General First Aid" section. Specific First Aid: Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024) Source: CAMEO Chemicals
- First Aid: In case of contact, immediately flush skin and eyes with plenty of water. Wash eyes at least 15 min. and get medical care. (USCG, 1999) Source: CAMEO Chemicals
- ERG2024, Guide 129 (Hexanols): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
- Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H226 (34.3%): Flammable liquid and vapor [Warning Flammable liquids]; H302+H312 (23.3%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]; H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (33.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H319 (35.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P210, P233, P240, P241, P242, P243, P264, P264+P265, P270, P280, P301+P317, P302+P352, P303+P361+P353, P305+P351+P338, P317, P321, P330, P337+P317, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 2711 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302+H312 (82.5%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]; H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (82.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H319 (82.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P317, P321, P330, P337+P317, P362+P364, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 126 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: NITE-CMC
- GHS Hazard Statements: H226: Flammable liquid and vapor [Warning Flammable liquids]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: NITE-CMC
- NFPA Health Rating: 3 - Materials that, under emergency conditions, can cause serious or permanent injury. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: An estimated BCF of 21 was calculated for 1-hexanol(SRC), using a log Kow of 2.03(1) and regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), a measured Koc value of 10.2(2), indicates that 1-hexanol is expected to have very high mobility in soil(SRC). Volatilization of 1-hexanol from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 1.71X10-5 atm-cu m/mole(3). 1-Hexanol is expected to volatilize slowly from dry soil surfaces(SRC) based upon a vapor pressure of 0.928 mm Hg(4). Biodegradation studies show that 1-hexanol is expected to degrade rapidly in both aerobic and anaerobic conditions(5-11). 1-Hexanol has aerobic, measured biodegradation half-lives of 0.36(8) and 1.7 days(9). Anaerobic, seven day biodegradation rates of 75%(10) and 83%(11) were measured for 1-hexanol. These rates suggest that biodegradation may be an important environmental fate process in soil(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), a Koc value of 10.2(2), indicates that 1-hexanol is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 1.71X10-5 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2 days and 20 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 21(SRC), from its log Kow of 2.03(6) and regression-derived equations(7), suggest the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation studies show that 1-hexanol is expected to degrade rapidly in both aerobic and anaerobic conditions(8-14). 1-Hexanol has aerobic, measured biodegradation half-lives of 0.36(11) and 1.7 days(12). Anaerobic, seven day biodegradation rates of 75%(13) and 83%(14) were measured for 1-hexanol. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1-hexanol, which has a vapor pressure of 0.928 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1-hexanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.3 days(SRC), calculated from its rate constant of 1.71X10-5 cu cm/molecule-sec at 25 °C(3). Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Lubricating agent; Flavoring and nutrient; Fuel; Monomers; Not Known or Reasonably Ascertainable; Fragrance Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Lubricating agent; Wetting agent (non-aqueous); Flavoring and nutrient; Solvent; Fuel; Surfactant (surface active agent); Monomers; Emulsifier; Fragrance; Intermediate Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used to produce plasticizers, antiseptics, fragrances, pharmaceuticals, and finishing agents for textile and leather; Used as a flavoring agent and a solvent for fats, waxes, dyes, and paints; [CHEMINFO] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Solvents) [Category: Paint] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: For 1-Hexanol (USEPA/OPP Pesticide Code: 079047) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
- Uses: The active ingredient is no longer contained in any registered pesticide products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
- Uses: Synthetic flavoring ingredient Source: Hazardous Substances Data Bank (HSDB)
- Uses: Pharmaceuticals (introduction of hexyl group into hyponics, antiseptics, perfume esters, etc), solvent, plasticizer, intermediate for textile and leather finishing agents. Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for 1-HEXANOL (12 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.