Official EU label nameGlossary entry 11493

GUANIDINE HCl

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:50-01-1

EC:200-002-3

Ingredient index records:

GUANIDINE HCL

Cosmetic functions: BUFFERING

Guanidinium chloride

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1 matched or reported name

GUANIDINE HCL

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GUANIDINE HCl.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 50-01-1

CAS 50-01-1PubChem CID 5742

Guanidine Hydrochloride

Guanidine Hydrochloride is the hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05) — NCI Thesaurus (NCIt)

IUPAC name: guanidine;hydrochloride

Molecular formula: CH6ClN3
Molecular weight: 95.53 g/mol
Exact mass: 95.0250249 Da
Topological polar surface area: 75.9 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 1
Covalent units: 2
Defined stereocentres: 0

Also known as

Guanidinium chlorideguanidine HClAminoformamidine hydrochlorideGUANIDINE MONOHYDROCHLORIDECarbamidine hydrochlorideAminomethanamidine hydrochlorideIminourea hydrochloride3YQC9ZY4YB

16 more reported names

NSC-755884Chloride, GuanidiniumGuanidium chlorideCHEBI:32735Chloride, GuanidiumHydrochloride, GuanidineRefChem:58639Monohydrochloride, Guanidine200-002-3Guanidine, monohydrochlorideGuanidine chlorideGuanidine (hydrochloride)GuanidinehydrochlorideCH6ClN3Guanidinium hydrochlorideGuanidine-13C hydrochloride

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External database identifiers

ChEMBL:CHEMBL1200728
EPA DTXSID:DTXSID7058757
PubMed:1117

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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