Official EU label nameGlossary entry 10973

GLAUCINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:475-81-0

EC:207-501-5

Ingredient index records:

GLAUCINE

Cosmetic functions: SKIN CONDITIONING

4H-Dibenzo[de,g]Quinoline,5,6,6a,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-,(6aS)-

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1 matched or reported name

GLAUCINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GLAUCINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 475-81-0

CAS 475-81-0PubChem CID 16754

(+)-Glaucine

(S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups. It has a role as an antibacterial agent, an antineoplastic agent, a platelet aggregation inhibitor, an antitussive, a muscle relaxant, a NF-kappaB inhibitor, a plant metabolite and a rat metabolite. It is an aporphine alkaloid, an organic heterotetracyclic compound, a polyether and a tertiary amino compound. It is a conjugate base of a (S)-glaucine(1+). — ChEBI

IUPAC name: (6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

Molecular formula: C21H25NO4
Molecular weight: 355.4 g/mol
Exact mass: 355.17835828 Da
XLogP3: 3.4
Topological polar surface area: 40.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 1

Also known as

GlaucineBromcholitinNSC-34396(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo(de,g)quinolineRefChem:4080575,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinolined-GlaucineBoldine dimethyl ether

16 more reported names

GlauventS-(+)-GlaucineGlaucine fumarate1,2,9,10-tetramethoxyaporphine1,2,9,10-Tetramethoxy-6a-alpha-aporphineNSC 34396(S)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolineGlaucine, dEINECS 207-501-5UNII-NU19306XA7(S)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinoline4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-, (S)-Tusidil (TN)Boldine dimethyletherGlaucine (Standard)GLAUCINE [MI]

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External database identifiers

ChEBI:CHEBI:5373
ChEMBL:CHEMBL228082
EPA DTXSID:DTXSID8031100
PubMed:22761149
PubMed:22737858
PubMed:22360330
PubMed:22056347
PubMed:20552526
PubMed:20101504
PubMed:20098607
PubMed:19592567
PubMed:19481591
PubMed:19400187
PubMed:18821489
PubMed:18590964

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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