Official EU label nameGlossary entry 10927

GEROTINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:71-44-3

EC:200-754-2

Ingredient index records:

GEROTINE

Cosmetic functions: SKIN CONDITIONING

N,N'-bis(3-aminopropyl)-1,4-butanediamine; Spermine; Gerontine

Inventory restriction note: II/411

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1 matched or reported name

GEROTINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GEROTINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 71-44-3

CAS 71-44-3PubChem CID 1103

Spermine

Spermine is a polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism. It has a role as an antioxidant, an immunosuppressive agent and a fundamental metabolite. It is a tetramine and a polyazaalkane. It is a conjugate base of a spermine(4+). — ChEBI

IUPAC name: N,N'-bis(3-aminopropyl)butane-1,4-diamine

Molecular formula: C10H26N4
Molecular weight: 202.34 g/mol
Exact mass: 202.21574685 Da
XLogP3: -1.1
Topological polar surface area: 76.1 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 0

Also known as

musculamineneuridinegerontineSperminN,N'-Bis(3-aminopropyl)-1,4-butanediamineDiaminopropyltetramethylenediamine4,9-Diaza-1,12-dodecanediamineSpermine, puriss

16 more reported names

1,4-Bis(aminopropyl)butanediamine1,4-Butanediamine, N,N'-bis(3-aminopropyl)-4,9-DiazadodecamethylenediamineGerotineSpermina4,9-Diazadodecane-1,12-diamine2FZ7Y3VOQXActilip sp-911,5,10,14-Tetraazatetradecane1,4-Bis(aminopropyl) butanediamine1,4-Diaminobutane, N,N'-bis(3-aminopropyl)-NSC-268508(3-aminopropyl)({4-[(3-aminopropyl)amino]butyl})amineCHEBI:15746diaminopropyl-tetramethylenediamine1,4-Butanediamine, N1,N4-bis(3-aminopropyl)-

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External database identifiers

ChEBI:CHEBI:15746
ChEMBL:CHEMBL23194
EPA DTXSID:DTXSID9058781
PubMed:37506855
PubMed:34085520
PubMed:27469509
PubMed:25911325
PubMed:25355561
PubMed:23707493
PubMed:23071598
PubMed:23057412
PubMed:23056524
PubMed:23054439
PubMed:23050262
PubMed:23022686

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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