
Disulfiram
Disulfiram is an organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. It has a role as a ferroptosis inducer, a fungicide, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an antineoplastic agent, an EC 3.1.1.8 (cholinesterase) inhibitor, an angiogenesis inhibitor, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an apoptosis inducer, a NF-kappaB inhibitor and an EC 3.1.1.1 (carboxylesterase) inhibitor. It is an organic disulfide and an organosulfur acaricide. — ChEBI
- IUPAC name
- diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate
- Molecular formula
- C10H20N2S4
- Molecular weight
- 296.5 g/mol
- Exact mass
- 296.05093334 Da
- XLogP3
- 3.9
- Topological polar surface area
- 121.0 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.