Why does CAS 7440-02-0 appear in more than one EU cosmetic annex?

A substance identified by CAS 7440-02-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 7440-02-0?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 7440-02-0 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 7440-02-0

Q: How do I use CAS 7440-02-0 for compliance screening?

Cross-reference CAS 7440-02-0 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

Q: What is the difference between a CAS number and an EC number?

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries.

CAS 7440-02-0 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7440-02-0

CAS 7440-02-0PubChem CID 935

Nickel

Nickel atom is chemical element (nickel group element atom) with atomic number 28. It has a role as a micronutrient and an epitope. It is a nickel group element atom and a metal allergen. — ChEBI

IUPAC name: nickel

Molecular formula: Ni
Molecular weight: 58.693 g/mol
Exact mass: 57.935342 Da
Topological polar surface area: 0.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 0
Covalent units: 1
Defined stereocentres: 0

Also known as

Metallic nickelFibrexNickel particlesFibrex PNiccolum metallicumNickel 200Nickel 201Nickel 205

16 more reported names

Nickel 207Nickel 270Alcan 756NINi 4303TNi 0901-SRCH 55/5NI 0901-S (harshaw)Ni 270CI 77775CHEBI:28112NICKEL METAL7OV03QG267C.I. 77775Dietary NickelRefChem:6057

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:28112
ChEBI:CHEBI:30399
EPA DTXSID:DTXSID2020925
EPA DTXSID:DTXSID20872443
PubMed:40250488
PubMed:39779229
PubMed:39326548
PubMed:38797200
PubMed:38605572
PubMed:38488660
PubMed:37418944
PubMed:37360515
PubMed:36794572
PubMed:36504304
PubMed:36073959
PubMed:35685677

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 7440-02-0

1 total

Annex

Entry

1093

Nickel; nickel powder [particle diameter<1 mm]

231-111-4

CMR

How CAS 7440-02-0 is used on this site

CAS 7440-02-0 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 7440-02-0 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 7440-02-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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Tools & next steps

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