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Annex II Entry 1093 CMR29/10/2010

Nickel; nickel powder [particle diameter<1 mm]

Nickel; nickel powder [particle diameter<1 mm] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1093
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 7440-02-0
CAS 7440-02-0PubChem CID 935

Nickel

Nickel atom is chemical element (nickel group element atom) with atomic number 28. It has a role as a micronutrient and an epitope. It is a nickel group element atom and a metal allergen. — ChEBI

IUPAC name
nickel
Molecular formula
Ni
Molecular weight
58.693 g/mol
Exact mass
57.935342 Da
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

Metallic nickelFibrexNickel particlesFibrex PNiccolum metallicumNickel 200Nickel 201Nickel 205
16 more reported names
Nickel 207Nickel 270Alcan 756NINi 4303TNi 0901-SRCH 55/5NI 0901-S (harshaw)Ni 270CI 77775CHEBI:28112NICKEL METAL7OV03QG267C.I. 77775Dietary NickelRefChem:6057
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Nickel; nickel powder [particle diameter<1 mm]

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

Other directives

(EC) 2009/790

SCCS opinions

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 2✓——

Key data

CAS
7440-02-0
EC
231-111-4
Annex
II
Entry number
1093

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1092
Nearby record in the same annex

Monocrotophos

CAS: 6923-22-4
EC: 230-042-7
Annex II 1088
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Fuel oil, no. 4

CAS: 68476-31-3
EC: 270-673-5
Annex II 1098
Nearby record in the same annex

Heptachlor

CAS: 76-44-8
EC: 200-962-3
Annex II 1087
Nearby record in the same annex

Fuel oil, no. 2

CAS: 68476-30-2
EC: 270-671-4

What Annex II means for Nickel; nickel powder [particle diameter<1 mm]

Nickel; nickel powder [particle diameter<1 mm] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Nickel; nickel powder [particle diameter<1 mm] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 7440-02-0 is the unique numerical identifier assigned to Nickel; nickel powder [particle diameter<1 mm] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Nickel; nickel powder [particle diameter<1 mm] has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Nickel; nickel powder [particle diameter<1 mm]

This page summarizes one Annex II record for Nickel; nickel powder [particle diameter<1 mm] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Nickel; nickel powder [particle diameter<1 mm], but confirm any final regulatory decision against the current official annex wording and source files.

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