
Sulfamethoxazole
Sulfamethoxazole is an isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. It has a role as an antimicrobial agent, an antibacterial agent, an antiinfective agent, a xenobiotic, a P450 inhibitor, an EC 2.5.1.15 (dihydropteroate synthase) inhibitor, an epitope, an EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor, an environmental contaminant and a drug allergen. It is a sulfonamide, a substituted aniline, a member of isoxazoles and a sulfonamide antibiotic. It is functionally related to a sulfanilamide. — ChEBI
- IUPAC name
- 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
- Molecular formula
- C10H11N3O3S
- Molecular weight
- 253.28 g/mol
- Exact mass
- 253.05211239 Da
- XLogP3
- 0.9
- Topological polar surface area
- 107.0 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 6
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.