Why does CAS 61-82-5 appear in more than one EU cosmetic annex?

A substance identified by CAS 61-82-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 61-82-5?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 61-82-5 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 61-82-5

Q: How do I use CAS 61-82-5 for compliance screening?

Cross-reference CAS 61-82-5 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 61-82-5 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 61-82-5

CAS 61-82-5PubChem CID 1639

Amitrole

Amitrole is a member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties. It has a role as a carotenoid biosynthesis inhibitor, a herbicide and an EC 1.11.1.6 (catalase) inhibitor. It is an aromatic amine and a member of triazoles. — ChEBI

IUPAC name: 1H-1,2,4-triazol-5-amine

Molecular formula: C2H4N4
Molecular weight: 84.08 g/mol
Exact mass: 84.043596145 Da
XLogP3: -0.4
Topological polar surface area: 67.6 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

3-amino-1,2,4-triazole1H-1,2,4-Triazol-3-amineAminotriazole3-AminotriazoleAmitrolAmizol3-Amino-1H-1,2,4-triazole3-Amino-s-triazole

16 more reported names

WeedazolAmerolCytrolCytroleEmisolVoroxAzaplantHerbizoleTriazolamineWeedazinWeedoclorAzolanElmasilFenavarAzaplant kombiHerbidal total

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:40036
ChEMBL:CHEMBL232801
EPA DTXSID:DTXSID0020076
PubMed:22984242
PubMed:22954362
PubMed:22879895
PubMed:22675500
PubMed:22670226
PubMed:22645569
PubMed:22639582
PubMed:22634845
PubMed:22590320
PubMed:22567327
PubMed:22558408
PubMed:22536190

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 61-82-5

1 total

Annex

Entry

1081

Amitrole (ISO)

200-521-5

CMR

How CAS 61-82-5 is used on this site

CAS 61-82-5 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 61-82-5 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 61-82-5 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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