
Idebenone
Idebenone is a member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia. It has a role as a ferroptosis inhibitor and an antioxidant. It is a member of 1,4-benzoquinones and a primary alcohol. — ChEBI
- IUPAC name
- 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
- Molecular formula
- C19H30O5
- Molecular weight
- 338.4 g/mol
- Exact mass
- 338.20932405 Da
- XLogP3
- 4.3
- Topological polar surface area
- 72.8 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 5
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:31687
- ChEMBL:CHEMBL252556
- EPA DTXSID:DTXSID0040678
- PubMed:34175429
- PubMed:31969611
- PubMed:28648635
- PubMed:21599003
- PubMed:14642398
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.