
Diphenoxylate Hydrochloride
Diphenoxylate Hydrochloride is the hydrochloride salt form of diphenoxylate, a piperidine derivate, chemically related to narcotic meperidine, with antidiarrheal activity and devoid of central nervous system (CNS) activity. Diphenoxylate acts on opioid receptors in the gastrointestinal tract, thereby decreasing gastrointestinal motility and causing constipation or preventing diarrhea. — NCI Thesaurus (NCIt)
- IUPAC name
- ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate;hydrochloride
- Molecular formula
- C30H33ClN2O2
- Molecular weight
- 489.0 g/mol
- Exact mass
- 488.2230560 Da
- Topological polar surface area
- 53.3 Ų
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 4
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEMBL:CHEMBL1200665
- EPA DTXSID:DTXSID3047843
Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.