Why does CAS 38083-17-9 appear in more than one EU cosmetic annex?

A substance identified by CAS 38083-17-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 38083-17-9?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 38083-17-9 to screen it directly, then review every linked annex record and supplier document.

CAS 2 records

CAS 38083-17-9

Q: How do I use CAS 38083-17-9 for compliance screening?

Cross-reference CAS 38083-17-9 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 38083-17-9 matches 2 EU annex records across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 38083-17-9

CAS 38083-17-9PubChem CID 37907

Climbazole

1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one is a ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3. It is a hemiaminal ether, a ketone, a member of imidazoles, an aromatic ether and a member of monochlorobenzenes. — ChEBI

IUPAC name: 1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one

Molecular formula: C15H17ClN2O2
Molecular weight: 292.76 g/mol
Exact mass: 292.0978555 Da
XLogP3: 3.7
Topological polar surface area: 44.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

ClimbazolBaypivalCrinipan ADBAY-E 6975BaysanClimbazolum2-Butanone, 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-NSC-759808

16 more reported names

9N42CW7I541-(p-Chlorophenoxy)-1-imidazol-1-yl-3,3-dimethyl-2-butanone(RS)-1-(4-CHLOROPHENOXY)-1-IMIDAZOL-1-YL-3,3-DIMETHYLBUTAN-2-ONERefChem:577718CHEBI:83499253-775-41-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one1-(4-Clorophenoxy)-3,3-dimethyl-1-(imidazole-1-yl)-2-butanone1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanoneClimbazol [INN-Spanish]Climbazolum [INN-Latin]CAS-38083-17-9Climbazole [INN:BAN]EINECS 253-775-4BRN 0618020Bay e 6975

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:83719
ChEMBL:CHEMBL1437764
EPA DTXSID:DTXSID6046555
PubMed:38795739
PubMed:21272039
PubMed:11824557
PubMed:11552297
PubMed:11534318

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 38083-17-9

2 total

Annex

Entry

CLIMBAZOLE

1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one

(a) Hair lotions (b) Face creams (c) Foot care products (d) Rinse-off shampoo

253-775-4

Max concentration

How CAS 38083-17-9 is used on this site

CAS 38083-17-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 2 EU annex records share this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 38083-17-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 38083-17-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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