Why does CAS 348635-87-0 appear in more than one EU cosmetic annex?

A substance identified by CAS 348635-87-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

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Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 348635-87-0 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 348635-87-0

Q: How do I use CAS 348635-87-0 for compliance screening?

Cross-reference CAS 348635-87-0 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 348635-87-0 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 348635-87-0

CAS 348635-87-0PubChem CID 10238657

Amisulbrom

Amisulbrom is a member of the class of bromoindoles that is 3-bromo-6-fluoro-2-methylindole substituted at position 1 by a 1-(dimethylsulfamyl)-1,2,4-triazole-3-sulfonyl group. A fungicide for use on potatoes to control late blight (Phytophthora infestans) and downy mildew [Plasmopara viticola). It has a low mammalian toxicity but it is considered to be a reproduction toxicant, is moderately toxic to birds and honey bees but poses a greater risk to aquatic species and earthworms. It has a role as a mitochondrial cytochrome-bc1 complex inhibitor and an antifungal agrochemical. It is a sulfonamide, a member of triazoles, an organofluorine compound, a member of sulfamides, a bromoindole, a sulfonamide fungicide and a triazole fungicide. — ChEBI

IUPAC name: 3-(3-bromo-6-fluoro-2-methylindol-1-yl)sulfonyl-N,N-dimethyl-1,2,4-triazole-1-sulfonamide

Molecular formula: C13H13BrFN5O4S2
Molecular weight: 466.3 g/mol
Exact mass: 464.95764 Da
XLogP3: 2.4
Topological polar surface area: 124.0 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 8
Covalent units: 1
Defined stereocentres: 0

Also known as

AmibromdoleLEIMAYRM460IQC3A3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamideNC-224CHEBI:818461H-1,2,4-triazole-1-sulfonamide, 3-((3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl)-N,N-dimethyl-1H-1,2,4-Triazole-1-sulfonamide, 3-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl-

16 more reported names

RefChem:1121013-((3-Bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamideAmisulbrom [ISO]UNII-RM460IQC3AHSDB 8031C13H13BrFN5O4S23-[(3-bromo-6-fluoro-2-methyl-1H-indol-1-yl)sulfonyl]-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamideAMISULBROM [MI]BREATYVWRHIPIY-UHFFFAOYSA-N3-(3-bromo-6-fluoro-2-methyl-indol-1-yl)sulfonyl-N,N-dimethyl-1,2,4-triazole-1-sulfonamideAmisulbrom 100 |Ig/mL in AcetonitrileAC-27458Amisulbrom 100 microg/mL in AcetonitrileDS-10929HY-121214CS-0081242

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:81846
EPA DTXSID:DTXSID0058063

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 348635-87-0

1 total

Annex

Entry

1623

Amisulbrom (ISO)3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1H-1,2,4-triazole-1-sulfonamide

672-776-4

CMR

How CAS 348635-87-0 is used on this site

CAS 348635-87-0 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 348635-87-0 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 348635-87-0 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

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